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. 1988 Sep-Oct;51(5):874-8.
doi: 10.1021/np50059a010.

Metabolism of homoorientin by human intestinal bacteria

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Metabolism of homoorientin by human intestinal bacteria

M Hattori et al. J Nat Prod. 1988 Sep-Oct.

Abstract

As a part of our studies on the metabolism of bioactive compounds from oriental medicines by intestinal flora, homoorientin, a C-glycosylflavonoid, was anaerobically incubated with a human intestinal bacterial mixture. Homoorientin was transformed to 6-C-glucosyleriodictyol, (+/-)-eriodictyol, luteolin, 3,4-dihydroxyphenylpropionic acid, and phloroglucinol. A novel cleavage of the C-glycosyl bond was discovered for the first time by using intestinal bacteria.

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