Tracing the Origin of Invasive Fungal Infections
- PMID: 32044130
- DOI: 10.1016/j.tim.2020.01.007
Tracing the Origin of Invasive Fungal Infections
Abstract
Invasive fungal infections are a major cause of mortality in immunocompromised patients. By using high-resolution sequencing, Zhai et al. provide insight into translocation of Candida strains from the gut mycobiota to the bloodstream of transplanted patients. Microbiota-driven diagnostic methods could rapidly emerge for preventing deadly fungal infections.
Keywords: bloodstream infections; dysbiosis; high-resolution sequencing; invasive candidiasis; mycobiota.
Copyright © 2020 Elsevier Ltd. All rights reserved.
Comment on
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High-resolution mycobiota analysis reveals dynamic intestinal translocation preceding invasive candidiasis.Nat Med. 2020 Jan;26(1):59-64. doi: 10.1038/s41591-019-0709-7. Epub 2020 Jan 6. Nat Med. 2020. PMID: 31907459 Free PMC article.
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