Does sequencing order of antiandrogens in prostate cancer matter?
- PMID: 32047281
- DOI: 10.1038/s41585-020-0289-9
Does sequencing order of antiandrogens in prostate cancer matter?
Comment on
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Optimal sequencing of enzalutamide and abiraterone acetate plus prednisone in metastatic castration-resistant prostate cancer: a multicentre, randomised, open-label, phase 2, crossover trial.Lancet Oncol. 2019 Dec;20(12):1730-1739. doi: 10.1016/S1470-2045(19)30688-6. Epub 2019 Nov 11. Lancet Oncol. 2019. PMID: 31727538 Clinical Trial.
References
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- Khalaf, D. J. et al. Optimal sequencing of enzalutamide and abiraterone acetate plus prednisone in metastatic castration-resistant prostate cancer: a multicentre, randomised, open-label, phase 2, crossover trial. Lancet Oncol. 20, 1730–1739 (2019). - DOI
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- Terada, N. Exploring the optimal sequence of abiraterone and enzalutamide in patients with chemotherapy-naive castration-resistant prostate cancer: the Kyoto-Baltimore collaboration. Int. J. Urol. 24, 441–448 (2017). - DOI
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- Brasso, K. Enzalutamide antitumour activity against metastatic castration-resistant prostate cancer previously treated with docetaxel and abiraterone: a multicentre analysis. Eur. Urol. 68, 317–324 (2015). - DOI
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- Maughan, B. L. & Antonarakis, E. S. Androgen pathway resistance in prostate cancer and therapeutic implications. Expert Opin. Pharmacother. 16, 1521–1537 (2015). - DOI
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- Isaacsson Velho, P. et al. Wnt-pathway activating mutations are associated with resistance to first-line abiraterone and enzalutamide in castration-resistant prostate cancer. Eur. Urol. 77, 14–21 (2020). - DOI
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