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. 2020 May;46(5):1050-1051.
doi: 10.1007/s00134-020-05940-8. Epub 2020 Feb 11.

Severe acute kidney injury is independently associated with mortality in children with septic shock

Natalja L Stanski  1 , Natalie Z Cvijanovich  2 , Julie C Fitzgerald  3 , Michael T Bigham  4 , Hector R Wong  5   6 ; Genomics of Pediatric Septic Shock Investigators
Collaborators, Affiliations

Severe acute kidney injury is independently associated with mortality in children with septic shock

Natalja L Stanski et al. Intensive Care Med. 2020 May.
No abstract available

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Conflict of interest statement

Conflicts of Interest: H.R.W. and the Cincinnati Children’s Hospital Research Foundation hold U.S. patents for the PERSEVERE biomarkers. All other authors: no conflict of interest.

Figures

Fig. 1
Fig. 1
28-day survival curves (a) and median number of PICU free days (b) by severity of SA-AKI at day 3 of septic shock
See this image and copyright information in PMC

References

    1. Kaddourah A, Basu RK, Bagshaw SM, et al. (2017) Epidemiology of Acute Kidney Injury in Critically Ill Children and Young Adults. N Engl J Med 376:11–20. 10.1056/NEJMoa1611391 - DOI - PMC - PubMed
    1. Fitzgerald JC, Basu RK, Akcan-Arikan A, et al. (2016) Acute Kidney Injury in Pediatric Severe Sepsis: An Independent Risk Factor for Death and New Disability. Crit Care Med 44:2241–2250. 10.1097/CCM.0000000000002007 - DOI - PMC - PubMed
    1. Weiss SL, Fitzgerald JC, Pappachan J, et al. (2015) Global epidemiology of pediatric severe sepsis: the sepsis prevalence, outcomes, and therapies study. Am J Respir Crit Care Med 191:1147–1157. 10.1164/rccm.201412-2323OC - DOI - PMC - PubMed
    1. Wong HR, Caldwell JT, Cvijanovich NZ, et al. (2019) Prospective clinical testing and experimental validation of the Pediatric Sepsis Biomarker Risk Model. Science Translational Medicine 11:. 10.1126/scitranslmed.aax9000 - DOI - PMC - PubMed
    1. Stanski NL, Wong HR (2020) Acute Kidney Injury is Independently Associated with Poor Outcomes in Children with Septic Shock. Abstract accepted at the 49th Critical Care Congress, Orlando, Florida, February 16–19, 2020.