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. 2020 Apr;165(4):955-958.
doi: 10.1007/s00705-020-04549-y. Epub 2020 Feb 11.

Viral metagenomics reveals sapoviruses of different genogroups in stool samples from children with acute gastroenteritis in Jiangsu, China

Wang Li  1   2 , Surong Dong  1   2 , Juan Xu  1   2 , Xiaobin Zhou  1   2 , Junling Han  1   2 , Zhaqing Xie  1   2 , Qin Gong  1   2 , Hailin Peng  1   2 , Chenglin Zhou  3   4 , Mei Lin  5   6
Affiliations

Viral metagenomics reveals sapoviruses of different genogroups in stool samples from children with acute gastroenteritis in Jiangsu, China

Wang Li et al. Arch Virol. 2020 Apr.

Abstract

Sapoviruses (SAVs), including several genogroups (GI to GV), are one of the causes of acute gastroenteritis (AGE). In this study, viral metagenomics revealed the presence of sapoviruses of different genogroups in stool from children with AGE. Eight different complete SAV genomes were determined, of which five belonged to GI and the other three belonged to GII, GIV and GV, respectively. Although they were highly similar to published sequences, the GIV and GV were the first complete genome sequences of these SAVs found in China. In a prevalence investigation, 19% of subjects with AGE were positive for SAVs, while none of the control group was positive.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Virome composition and phylogeny. Virome composition in fecal samples from children with and without AGE. (B) Phylogenetic analysis based on the complete genome. (C) Phylogenetic analysis based on VP1 region
See this image and copyright information in PMC

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