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. 2020 Feb 7:18:AE4530.
doi: 10.31744/einstein_journal/2020AE4530. eCollection 2020.

Brazilian Nutritional Consensus in Hematopoietic Stem Cell Transplantation: Adults

[Article in English, Portuguese]
Affiliations

Brazilian Nutritional Consensus in Hematopoietic Stem Cell Transplantation: Adults

[Article in English, Portuguese]
Juliana Bernardo Barban et al. Einstein (Sao Paulo). .

Abstract

The nutritional status of patients submitted to hematopoietic stem cell transplant is considered an independent risk factor, which may influence on quality of life and tolerance to the proposed treatment. The impairment of nutritional status during hematopoietic stem cell transplant occurs mainly due to the adverse effects resulting from conditioning to which the patient is subjected. Therefore, adequate nutritional evaluation and follow-up during hematopoietic stem cell transplant are essential. To emphasize the importance of nutritional status and body composition during treatment, as well as the main characteristics related to the nutritional assessment of the patient, the Brazilian Consensus on Nutrition in Hematopoietic Stem Cell Transplant: Adults was prepared, aiming to standardize and update Nutritional Therapy in this area. Dietitians, nutrition physicians and hematologists from 15 Brazilian centers thar are references in hematopoietic stem cell transplant took part.

RESUMO: O estado nutricional do paciente submetido ao transplante de células-tronco hematopoéticas é considerado fator de risco independente, podendo influenciar na qualidade de vida e na tolerância ao tratamento proposto. O comprometimento do estado nutricional durante o transplante de células-tronco hematopoéticas ocorre principalmente devido aos efeitos adversos decorrentes do condicionamento ao qual o paciente é submetido. Desta forma, a adequada avaliação nutricional e o acompanhamento durante o transplante de células-tronco hematopoéticas tornam-se imprescindíveis. Com o objetivo de salientar a importância do estado nutricional e da composição corporal durante o tratamento, bem como as principais características relacionadas à avaliação nutricional do paciente, o Consenso Brasileiro de Nutrição em Transplante de Células-Tronco Hematopoiéticas: Adulto foi elaborado visando uniformizar e atualizar a Terapia Nutricional nesta área. Com a participação de nutricionistas, nutrólogos e hematologistas de 15 centros brasileiros referências em transplante de células-tronco hematopoéticas

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Conflict of interest statement

Conflict of interest: none.

Figures

Figure 1
Figure 1. Flow chart for decision-making regarding admission for hematopoietic stem cell transplantation
SGA: Subjective Global Assessment; PG-SGA: Patient-Generated Subjective Global Assessment; RDA: Recommended Daily Allowance; ONT: oral nutrition therapy; EN: enteral nutrition; GVHD: graft-versus-host disease; PNT: parenteral nutrition therapy.
Figure 2
Figure 2. Flow chart for decision-making in nutritional assessment before hematopoietic stem cell transplant (HSCT)
SGA: Subjective Global Assessment; PG-SGA: Patient-Generated Subjective Global Assessment; IAB: intraaortic balloon; US: ultrasound; ONT: oral nutrition therapy; EN: enteral nutrition.
Figura 1
Figura 1. Fluxograma para tomada de decisão em admissão para o transplante de células-tronco hematopoéticas
ASG: Avaliação Subjetiva Global; ASG-PPP: Avaliação Subjetiva Global Produzida pelo Paciente; IDR: Ingestão Dietética Recomendada TNO: terapia nutricional oral; TNE: terapia nutricional enteral; DECH: doença do enxerto contra o hospedeiro; TNP: terapia nutricional parenteral.
Figura 2
Figura 2. Fluxograma para tomada de decisão em avaliação nutricional pré-transplante de células-tronco hematopoéticas (TCTH)
ASG: Avaliação Subjetiva Global; ASG-PPP: Avaliação Subjetiva Global Produzida pelo Próprio Paciente; BIA: balão intra-aórtico; USG: ultrassonografia; TNO: terapia nutricional oral; TNE: terapia nutricional enteral.

References

    1. 1. Copelan EA. Hematopoietic stem-cell transplantation. N Engl J Med. 2006; 354(17):1813-26. - PubMed
    2. Copelan EA. Hematopoietic stem-cell transplantation. N Engl J Med. 2006;354(17):1813–1826. - PubMed
    1. 2. Majhail NS, Rizzo JD, Lee SJ, Aljurf M, Atsuta Y, Bonfim C, Burns LJ, Chaudhri N, Davies S, Okamoto S, Seber A, Socie G, Szer J, Van Lint MT, Wingard JR, Tichelli A; Center for International Blood and Marrow Transplant Research (CIBMTR); American Society for Blood and Marrow Transplantation (ASBMT); European Group for Blood and Marrow Transplantation (EBMT); Asia-Pacific Blood and Marrow Transplantation Group (APBMT); Bone Marrow Transplant Society of Australia and New Zealand (BMTSANZ); East Mediterranean Blood and Marrow Transplantation Group (EMBMT),; Sociedade Brasileira de Transplante de Medula Ossea (SBTMO). Recommended screening and preventive practices for long-term survivors after hematopoietic cell transplantation. Biol Blood Marrow Transplant. 2012;18(3):348–71. - PubMed
    2. Majhail NS, Rizzo JD, Lee SJ, Aljurf M, Atsuta Y, Bonfim C, Burns LJ, Chaudhri N, Davies S, Okamoto S, Seber A, Socie G, Szer J, Van Lint MT, Wingard JR, Tichelli A, Center for International Blood and Marrow Transplant Research (CIBMTR) American Society for Blood and Marrow Transplantation (ASBMT) European Group for Blood and Marrow Transplantation (EBMT) Asia-Pacific Blood and Marrow Transplantation Group (APBMT) Bone Marrow Transplant Society of Australia and New Zealand (BMTSANZ) East Mediterranean Blood and Marrow Transplantation Group (EMBMT) Sociedade Brasileira de Transplante de Medula Ossea (SBTMO) Recommended screening and preventive practices for long-term survivors after hematopoietic cell transplantation. Biol Blood Marrow Transplant. 2012;18(3):348–371. - PMC - PubMed
    1. 3. Associação Brasileira de Transplante de Órgãos (ABTO). Registro Brasileiro de Transplantes (RBT). Dimensionamento dos transplantes no Brasil e em cada estado 2011-2018 [Internet]. São Paulo (SP): ABTO; 2018 [citado 2019 Jun 25]. Disponível em: http://www.abto.org.br/abtov03/Upload/file/RBT/2018/Lv_RBT-2018.pdf
    2. Associação Brasileira de Transplante de Órgãos (ABTO) Registro Brasileiro de Transplantes (RBT). Dimensionamento dos transplantes no Brasil e em cada estado 2011-2018. São Paulo (SP): ABTO; 2018. [citado 2019 Jun 25]. Internet. http://www.abto.org.br/abtov03/Upload/file/RBT/2018/Lv_RBT-2018.pdf.
    1. 4. Instituto Nacional do Câncer (INCA). Medula Net. Redome [Internet]. Rio de Janeiro: INCA: 2013 [citado 2019 Jun 27]. Disponível em: http://redome.inca.gov.br/o-redome/dados/
    2. Instituto Nacional do Câncer (INCA) Medula Net. Redome. Rio de Janeiro: INCA; 2013. [citado 2019 Jun 27]. Internet. http://redome.inca.gov.br/o-redome/dados/
    1. 5. Passweg JR, Halter J, Bucher C, Gerull S, Heim D, Rovó A, et al. Hematopoietic stem cell transplantation: a review and recommendations for follow-up care for the general practitioner. Swiss Med Wkly. 2012;142:w13696. Review. - PubMed
    2. Passweg JR, Halter J, Bucher C, Gerull S, Heim D, Rovó A, et al. Hematopoietic stem cell transplantation: a review and recommendations for follow-up care for the general practitioner. Swiss Med Wkly. 2012;142:w13696. Review. - PubMed

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