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Comment
. 2020 May 15;201(10):1310-1311.
doi: 10.1164/rccm.202001-0050LE.

Bacterial DNA in Fetal Lung Samples May Be Explained by Sample Contamination

Wouter A A de Steenhuijsen Piters  1   2 , Debby Bogaert  1   2   3
Affiliations
Comment

Bacterial DNA in Fetal Lung Samples May Be Explained by Sample Contamination

Wouter A A de Steenhuijsen Piters et al. Am J Respir Crit Care Med. .
No abstract available

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Comment in

Comment on

  • Human Fetal Lungs Harbor a Microbiome Signature.
    Al Alam D, Danopoulos S, Grubbs B, Ali NABM, MacAogain M, Chotirmall SH, Warburton D, Gaggar A, Ambalavanan N, Lal CV. Al Alam D, et al. Am J Respir Crit Care Med. 2020 Apr 15;201(8):1002-1006. doi: 10.1164/rccm.201911-2127LE. Am J Respir Crit Care Med. 2020. PMID: 31898918 Free PMC article. No abstract available.

References

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    1. de Goffau MC, Lager S, Sovio U, Gaccioli F, Cook E, Peacock SJ, et al. Human placenta has no microbiome but can contain potential pathogens. Nature. 2019;572:329–334. - PMC - PubMed
    1. Aagaard K, Ma J, Antony KM, Ganu R, Petrosino J, Versalovic J. The placenta harbors a unique microbiome. Sci Transl Med. 2014;6:237ra65. - PMC - PubMed
    1. Salter SJ, Cox MJ, Turek EM, Calus ST, Cookson WO, Moffatt MF, et al. Reagent and laboratory contamination can critically impact sequence-based microbiome analyses. BMC Biol. 2014;12:87. - PMC - PubMed
    1. Arck PC, Hecher K. Fetomaternal immune cross-talk and its consequences for maternal and offspring’s health. Nat Med. 2013;19:548–556. - PubMed