Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Feb 12;21(1):95.
doi: 10.1186/s12891-020-3100-4.

Venous thromboembolism rates after hip and knee arthroplasty and hip fractures

Affiliations

Venous thromboembolism rates after hip and knee arthroplasty and hip fractures

Viswanath Mula et al. BMC Musculoskelet Disord. .

Abstract

Background: The ideal thromboprophylaxis regime following lower limb arthroplasty and proximal femur fractures remains controversial. Guidelines disagree on the type of chemical prophylaxis, its dose or duration. This article describes a method of monitoring venous thromboembolism (VTE) rates following Total Hip (THA), Total Knee Arthroplasty (TKA) and surgery for hip fractures (NOF#).

Methods: Over 3 years, all patients investigated for VTE were analysed using Picture Archiving Communications System (PACS). All positive scans were then cross-referenced using PACS and local registry data to see if they had undergone THA, TKA or NOF# in the preceding 90 days. Mortality data were obtained from the national administrative database, Hospital Episode Statistics.

Results: Five thousand seven hundred eighty-eight patients underwent investigation for VTE and there were 29 diagnoses of PE and 24 of DVT. There was a 0.77% rate of symptomatic DVT after THA, 0.05% after TKA and 0.55% after NOF #. The rate of confirmed symptomatic PE for THA was 0.46, 0.27% for TKA and 0.96% for NOF #. Mortality at one-year post-THA was 0.6, 0.6% for TKA and 25.9% after NOF#. All patients contacted either remained within the catchment area for the minimum 90 postoperative days or died within the catchment area.

Conclusions: The 90 day post-operative prevalence of symptomatic VTE of 1.2, 0.3 and 1.5% in THA, TKA and NOF # respectively are similar to other studies using symptomatic and imaging positive VTE as their endpoint. The study uses a method of collecting data which can be utilised in centres where PACS is available.

Keywords: Hip fractures; PACS; THA; TKA; VTE.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
A flow chart explaining the sequence for calculating the rate of postoperative 90 day VTE. The blue boxes show the 3 stages in the collection of data to calculate the VTE rates. The 2 white boxes show how the method was validated

References

    1. No authors listed. National Institute for Health and Clinical Excellence. Venous Thromboembolism; reducing the risk of venous thromboembolism (deep vein thrombosis and pulmonary embolism) in inpatients admitted to hospital: methods, evidence and guidance. 2010 http://www.nice.org.uk/nicemedia/live/12695/47920/47920.pdf.
    1. Geerts WH, Heit JA, Clagett GP, Colwell CW, Anderson FA, Jr, Wheeler HB. Prevention of venous thromboembolism. Chest. 2001;119:132S–175S. doi: 10.1378/chest.119.1_suppl.132S. - DOI - PubMed
    1. Warwick D, Dahl OE, Fisher WD. Orthopaedic thromboprophylaxis: limitations of current guidelines. J Bone Joint Surg (Br) 2008;90:127–132. doi: 10.1302/0301-620X.90B2.20106. - DOI - PubMed
    1. Haas SB, Barrack RL, Westrich G, Lachiewicz PF. Venous thromboembolic disease after total hip and knee arthroplasty. J Bone Joint Surg Am. 2008;90(12):2764–2780. - PubMed
    1. Burnett RS, Clohisy JC, Wright RW, McDonald DJ, Shively RA, Givens SA, Barrack RL. Failure of the American College of Chest Physicians-1A protocol for lovenox in clinical outcomes for thromboembolic prophylaxis. J Arthroplast. 2007;22(3):317–324. doi: 10.1016/j.arth.2007.01.007. - DOI - PubMed

MeSH terms