With haemoglobin as with politics - should we shift right or left?
- PMID: 32052863
- DOI: 10.1113/JP279555
With haemoglobin as with politics - should we shift right or left?
Keywords: O2 transport; high altitude hypoxia; high vs low HbO2 affinity.
Comment on
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Influence of high affinity haemoglobin on the response to normoxic and hypoxic exercise.J Physiol. 2020 Apr;598(8):1475-1490. doi: 10.1113/JP279161. Epub 2020 Feb 11. J Physiol. 2020. PMID: 31923331 Free PMC article.
References
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- Barcroft J, Binger CA, Bock AV, Doggart JH, Forbes HS, Harrup G, Meakins JC, Redfield AC, Davies HW, Duncan Scott JM, Fetter WJ, Murray CD & Keith A (1923). Observations upon the effect of high altitude on the physiological process of the human body carried out in the Peruvian Andes, chiefly at Cerro de Pasco. Philos Trans R Soc Lond B Biol Sci 211, 351-480.
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- Dominelli PB, Wiggins CC, Baker SE, Shepherd JRA, Roberts SK, Roy TK, Curry TB, Hoyer JD, Oliveira JL & Joyner MJ (2020). Influence of high affinity hemoglobin on the response to normoxic and hypoxic exercise. J Physiol 598, 1475-1490.
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- Storz JF (2016). Hemoglobin-oxygen affinity in high altitude vertebrates: Is there evidence for an adaptive trend? J Exp Biol 219, 3190-3203.
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- Winslow RP (2007). Role of hemoglobin-oxygen affinity in O2 transport at high altitude. Respir Physiol Neurobiol 158, 121-127.
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- Woodson R & Auerbach S (1982). Effect of increased HbO2 affinity and anemia on cardiac output and its distribution. J Appl Physiol 53, 1299-1306.
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