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Comment
. 2020 Feb 12;27(2):169-172.
doi: 10.1016/j.chom.2020.01.022.

Therapeutics Targeting the Gut Microbiome: Rigorous Pipelines for Drug Development

Kate A Markey  1 , Marcel R M van den Brink  2 , Jonathan U Peled  3
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Comment

Therapeutics Targeting the Gut Microbiome: Rigorous Pipelines for Drug Development

Kate A Markey et al. Cell Host Microbe. .
Free article

Abstract

Restoration of the gut microbiome is a promising preventive and therapeutic strategy in a number of clinical scenarios. We discuss here the scientific and clinical challenges of engineering and implementing these strategies.

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Conflict of interest statement

Declaration of Interests M.R.M.v.d.B. has received research support from Seres Therapeutics; has consulted, received honorarium from, or participated in advisory boards for Seres Therapeutics, Flagship Ventures, Novartis, Evelo, Jazz Pharmaceuticals, Therakos, Amgen, Magenta Therapeutics, WindMIL Therapeutics, Merck & Co, Inc., Acute Leukemia Forum (ALF), and DKMS Medical Council (Board); and has IP Licensing with Seres Therapeutics and Juno Therapeutics. J.U.P. reports research funding, intellectual property fees, and travel reimbursement from Seres Therapeutics and consulting fees from DaVolterra.

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