Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Aug;32(8):1443-1450.
doi: 10.1007/s40520-020-01500-8. Epub 2020 Feb 13.

Does self-report of multimorbidity in later life predict impaired physical functioning, and might this be useful in clinical practice?

Affiliations

Does self-report of multimorbidity in later life predict impaired physical functioning, and might this be useful in clinical practice?

Michael A Clynes et al. Aging Clin Exp Res. 2020 Aug.

Abstract

Background: Multimorbidity has been shown in several studies to relate to impaired physical function in later life.

Aims: To examine if self-report of multimorbidity predicts impaired physical functioning, as assessed by formal physical function testing, in community-dwelling older adults.

Methods: Non-communicable diseases (NCDs) were self-reported by 443 older community-dwelling UK adults via questionnaire, asking the question: 'Have you been told by a doctor that you have any of the following conditions?' Assessments of walking speed, chair stands and balance allowed us to create a composite score (0-12) on which impaired physical functioning was defined as ≤ 9.

Results: The mean age of participants was 75.5 ± 2.5 years for men and 75.8 ± 2.6 for women. The proportion of individuals with impaired physical functioning was 71.2% in women and 56.9% in men. Having four or more NCDs was associated with an increased risk of poor physical function in men and women (p < 0.05). The number of medications and medicated systems was associated with gait speed (p < 0.03 and < 0.02, respectively) and timed up-and-go tests (p < 0.03 and < 0.02, respectively) in women but not men.

Discussion and conclusion: Self-report of 4 or more NCDs was associated with an increased risk of poor physical function, an outcome which has previously been associated with adverse clinical sequelae. This observation may inform development of a simple screening tool to look for poor physical function in older adults.

Keywords: Ageing; Multimorbidity; Non-communicable diseases; Older people; Physical functioning.

PubMed Disclaimer

Conflict of interest statement

Professor Cyrus Cooper has received lecture fees and honoraria from Amgen, Danone, Eli Lilly, GSK, Kyowa Kirin, Medtronic, Merck, Nestlé, Novartis, Pfizer, Roche, Servier, Shire, Takeda and UCB outside of the submitted work. Professor Elaine Dennison has received speaker honoraria from UCB and Pfizer. Author Michael Clynes has received support for attending conferences from UCB, Pfizer and Eli Lily.

Similar articles

Cited by

References

    1. Prince MJ, Wu F, Guo Y, et al. The burden of disease in older people and implications for health policy and practice. Lancet. 2015;385:549–562. - PubMed
    1. Duffield SJ, Ellis BM, Goodson N, et al. The contribution of musculoskeletal disorders in multimorbidity: implications for practice and policy. Best Pract Res Clin Rheumatol. 2017;31:129–144. - PubMed
    1. Parreira PCS, Maher CG, Ferreira ML, et al. A longitudinal study of the influence of comorbidities and lifestyle factors on low back pain in older men. Pain. 2017;158:1571–1576. - PubMed
    1. Bayliss EA, Ellis JL, Steiner JF. Barriers to self-management and quality-of-life outcomes in seniors with multimorbidities. Ann Fam Med. 2007;5:395–402. - PMC - PubMed
    1. Fortin M, Bravo G, Hudon C, et al. Prevalence of multimorbidity among adults seen in family practice. Ann Fam Med. 2005;3:223–228. - PMC - PubMed

LinkOut - more resources