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Comment
. 2020 Feb;52(2):136-137.
doi: 10.1038/s41588-020-0577-6.

A small molecule kicks repeat expansion into reverse

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Comment

A small molecule kicks repeat expansion into reverse

Michael D Flower et al. Nat Genet. 2020 Feb.
No abstract available

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  • A slipped-CAG DNA-binding small molecule induces trinucleotide-repeat contractions in vivo.
    Nakamori M, Panigrahi GB, Lanni S, Gall-Duncan T, Hayakawa H, Tanaka H, Luo J, Otabe T, Li J, Sakata A, Caron MC, Joshi N, Prasolava T, Chiang K, Masson JY, Wold MS, Wang X, Lee MYWT, Huddleston J, Munson KM, Davidson S, Layeghifard M, Edward LM, Gallon R, Santibanez-Koref M, Murata A, Takahashi MP, Eichler EE, Shlien A, Nakatani K, Mochizuki H, Pearson CE. Nakamori M, et al. Nat Genet. 2020 Feb;52(2):146-159. doi: 10.1038/s41588-019-0575-8. Epub 2020 Feb 14. Nat Genet. 2020. PMID: 32060489 Free PMC article.

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