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. 2020 Apr;122(9):1275-1276.
doi: 10.1038/s41416-020-0738-5. Epub 2020 Feb 17.

New survival standards for advanced melanoma

Lavinia Spain  1   2   3 , James Larkin  1 , Samra Turajlic  4   5
Affiliations

New survival standards for advanced melanoma

Lavinia Spain et al. Br J Cancer. 2020 Apr.

Abstract

The expectation for survival in patients with advanced melanoma now exceeds 50% at 5 years in patients treated with first-line combination ipilimumab and nivolumab, despite this regimen being associated with substantial toxicity. We discuss the latest updates from the Checkmate-067 study, framing the role of this combination in practice today.

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Conflict of interest statement

S.T. reports grants and speaker fees from Roche Tissue Diagnostics. J.L. reports institutional research support from BMS, MSD, Novartis, Pfizer, Achilles Therapeutics, Roche, Nektar Therapeutics, Covance, Immunocore, Pharmacyclics and Aveo, and consultancy support from Achilles, AZ, Boston Biomedical, BMS, Eisai, EUSA Pharma, GSK, Ipsen, Imugene, Incyte, iOnctura, Kymab, Merck Serono, MSD, Nektar, Novartis, Pierre Fabre, Pfizer, Roche/Genentech, Secarna and Vitaccess. L.S. has no conflicts of interest to declare.

References

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