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Editorial
. 2020 May;71(5):1530-1532.
doi: 10.1002/hep.31189.

Acetaminophen Hepatotoxicity: Strong Offense and Weakened Defense

Neil Kaplowitz  1 , Tin Aung Than  1 , Sanda Win  1
Affiliations
Editorial

Acetaminophen Hepatotoxicity: Strong Offense and Weakened Defense

Neil Kaplowitz et al. Hepatology. 2020 May.
No abstract available

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References

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    1. Saito C, Lemasters JJ, Jaeschke H. c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicity. Toxicol Appl Pharmacol 2010;246:8-17.
    1. Jaeschke H, Akakpo JY, Umbaugh DS, Novel RA. Therapeutic approaches against acetaminophen-induced liver injury and acute liver failure. Toxicol Sci 2020 Jan 11. pii: kfaa002. https://doi.org/10.1093/toxsci/kfaa002. [Epub ahead of print]
    1. Hanawa N, Shinohara M, Saberi B, Gaarde WA, Han D, Kaplowitz N. Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injury. J Biol Chem 2008;283:13565-13577.

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