CD36 - the Achilles' heel of T_reg cells

Brendan L Horton¹, Stefani Spranger^{2

3

4}

Affiliations

¹ Koch Institute for Cancer Research at MIT, Massachusetts Institute of Technology, Cambridge, MA, USA.
² Koch Institute for Cancer Research at MIT, Massachusetts Institute of Technology, Cambridge, MA, USA. Spranger@mit.edu.
³ Biology Department, Massachusetts Institute of Technology, Cambridge, MA, USA. Spranger@mit.edu.
⁴ Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA. Spranger@mit.edu.

Comment

Brendan L Horton et al. Nat Immunol. 2020 Mar.

. 2020 Mar;21(3):251-253.

doi: 10.1038/s41590-020-0601-0.

Brendan L Horton¹, Stefani Spranger^{2

3

4}

¹ Koch Institute for Cancer Research at MIT, Massachusetts Institute of Technology, Cambridge, MA, USA.
² Koch Institute for Cancer Research at MIT, Massachusetts Institute of Technology, Cambridge, MA, USA. Spranger@mit.edu.
³ Biology Department, Massachusetts Institute of Technology, Cambridge, MA, USA. Spranger@mit.edu.
⁴ Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA. Spranger@mit.edu.

No abstract available

Comment on

CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors.
Wang H, Franco F, Tsui YC, Xie X, Trefny MP, Zappasodi R, Mohmood SR, Fernández-García J, Tsai CH, Schulze I, Picard F, Meylan E, Silverstein R, Goldberg I, Fendt SM, Wolchok JD, Merghoub T, Jandus C, Zippelius A, Ho PC. Wang H, et al. Nat Immunol. 2020 Mar;21(3):298-308. doi: 10.1038/s41590-019-0589-5. Epub 2020 Feb 17. Nat Immunol. 2020. PMID: 32066953 Free PMC article.

1. Horton, B. L. et al. Cancer Immunol. Res. 6, 14–24 (2018). - DOI
1. Wang, H. et al. Nat. Immunol. https://doi.org/10.1038/s41590-019-0589-5 (2020).
1. Jansen, C. S. et al. Nature 576, 465–470 (2019). - DOI
1. Spranger, S. et al. Sci. Transl. Med. 5, 200ra116 (2013). - DOI
1. Bos, P. D. et al. J. Exp. Med. 210, 2435–2466 (2013). - DOI