Advances in chronic intestinal failure management and therapies
- PMID: 32073503
- DOI: 10.1097/MOG.0000000000000631
Advances in chronic intestinal failure management and therapies
Abstract
Purpose of review: To summarize changes and recent advances in therapies for chronic intestinal failure (CIF).
Recent findings: In the last few years, the management of CIF has significantly improved through better prevention and treatment of catheter-related bloodstream infections (CRBSIs) and intestinal failure-associated liver disease (IFALD), as well as improved enteral autonomy by using small bowel growth factors in selected patients. This may have been reflected by a recent reduction in small bowel transplantations.
Summary: Although CIF management has become more established and effective, the long-term implications of parenteral nutrition still place substantial burden on patients such that further work is required to improve patients' quality of life as well as continued efforts to reduce complications relating to CIF management.
References
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- Pironi L, Konrad D, Brandt C, et al. Clinical classification of adult patients with chronic intestinal failure due to benign disease: An international multicenter cross-sectional survey. Clin Nutr 2018; 37:728–738.
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- Dibb M, Soop M, Teubner A, et al. Survival and nutritional dependence on home parenteral nutrition: three decades of experience from a single referral centre. Clin Nutr 2017; 36:570–576.
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- Lloyd DA, Vega R, Bassett P, et al. Survival and dependence on home parenteral nutrition: experience over a 25-year period in a UK referral centre. Aliment Pharmacol Ther 2006; 24:1231–1240.
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- Bond A, Soop M, Taylor M, et al. Home parenteral nutrition and the older adult: Experience from a national intestinal failure unit. Clin Nutr 2019; [Epub ahead of print].
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