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Observational Study
. 2020 Feb;9(1):e000882.
doi: 10.1136/bmjoq-2019-000882.

Quality improvement programme reduces errors in oral medication preparation and administration through feeding tubes

Affiliations
Observational Study

Quality improvement programme reduces errors in oral medication preparation and administration through feeding tubes

Rosana Aparecida Pereira et al. BMJ Open Qual. 2020 Feb.

Abstract

Background: Patients with nasogastric/nasoenteric tube (NGT/NET) are at increased risk of adverse outcomes due to errors occurring during oral medication preparation and administration.

Aim: To implement a quality improvement programme to reduce the proportion of errors in oral medication preparation and administration through NGT/NET in adult patients.

Methods: An observational study was carried out, comparing outcome measures before and after implementation of the integrated quality programme to improve oral medication preparation and administration through NGT/NET. A collaborative approach based on Plan-Do-Study-Act (PDSA) cycle was used and feedback was given during multidisciplinary meetings.

Interventions: Good practice guidance for oral medication preparation and administration through NGT/NET was developed and implemented at the hospital sites; nurses were given formal training to use the good practice guidance; a printed list of oral medications that should never be crushed was provided to all members of the multidisciplinary team, and a printed table containing therapeutic alternatives for drugs that should never be crushed was provided to prescribers at the prescribing room.

Results: Improvement was observed in the following measures: crushing enteric-coated tablets and mixing drugs during medication preparation (from 54.9% in phase I to 26.2% in phase II; p 0.0010) and triturating pharmaceutical form of modified action or dragee (from 32.8 in phase I to 19.7 in phase II; p 0.0010). Worsening was observed though in the following measures: crush compressed to a fine and homogeneous powder (from 7.4%% in phase I to 95% phase II; p 0.0010) and feeding tube obstruction (from 41.8% in phase I to 52.5% phase II; p 0.0950).

Conclusion: Our results highlight how a collaborative quality improvement approach based on PDSA cycles can meet the challenge of reducing the proportion of errors in oral medication preparation and administration through NGT/NET in adult patients. Some changes may lead to unintended consequences though. Thus, continuous monitoring for these consequences will help caregivers to prevent poor patient outcomes.

Keywords: PDSA; medication safety; quality improvement.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Quality improvement program phase II diagram. Cycles 1 and 2: two consecutive cycles were performed. The first served to elaborate the good practice guide for the preparation and administration of oral medication via NGT/ NET. The second was to offer training to the nursing staff. Cycle 3: the goal was to evaluate drug preparation and administration via NGT/ NET and compare the data with the baseline result. NGT/NET, nasogastric/nasoenteric tube; PDSA, Plan-Do-Study-Act.
Figure 2
Figure 2
Weekly statistical process control chart showing the percentage of crush compressed to a fine and homogeneous powder. Control chart showing the percentage of crush compressed to a fine and homogeneous powder. Administered to 16 patients reporting continuous observation and follow-up periods. Hospital elected to the improvement programme made changes to improve oral medication preparation and administration techniques via NGT/ NET. PDSA 3: We found that in the hospital there was no pestle mortar to crush the solid forms, it is clear that the process worsened. NGT/NET, nasogastric/nasoenteric tube; PDSA, Plan-Do-Study-Act.

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References

    1. van Riet-Nales DA, Schobben AFAM, Vromans H, et al. . Safe and effective pharmacotherapy in infants and preschool children: importance of formulation aspects. Arch Dis Child 2016;101:662–9. 10.1136/archdischild-2015-308227 - DOI - PMC - PubMed
    1. Romero Jiménez Rosa Mª, Ortega Navarro C, Cuerda Compés C. Polypharmacy and enteral nutrition in patients with complex chronic diseases. Nutr Hosp 2017;34:57–76. 10.20960/nh.1240 - DOI - PubMed
    1. Hens B, Corsetti M, Bermejo M, et al. . "Development of Fixed Dose Combination Products" Workshop Report: Considerations of Gastrointestinal Physiology and Overall Development Strategy. Aaps J 2019;21:75 10.1208/s12248-019-0346-6 - DOI - PubMed
    1. Anon Abstracts from the 2017 Society of general internal medicine annual meeting. J Gen Intern Med 2017;32:83–8. 10.1007/s11606-017-4028-8 - DOI - PMC - PubMed
    1. IHI How to improve. Cambridge, MA: Institute for Healthcare Improvement, 2016.

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