Optimal management of ascites
- PMID: 32077614
- DOI: 10.1111/liv.14361
Optimal management of ascites
Erratum in
-
ERRATUM.Liver Int. 2020 May;40(5):1247. doi: 10.1111/liv.14454. Liver Int. 2020. PMID: 32352236 No abstract available.
Abstract
Ascites is the most common complication of cirrhosis, which develops in 5%-10% of patients per year. Its management is based on symptomatic measures including restriction of sodium intake, diuretics and paracentesis. Underlying liver disease must always be treated and may improve ascites. In some patients, ascites is not controlled by medical therapies and has a major impact on quality of life and survival. TIPS placement and liver transplantation must therefore be discussed. More recently, repeated albumin infusions and Alfapump® have emerged as new therapies in ascites. In this review, the current data on these different options are analysed and an algorithm to help the physician make clinical decisions is suggested.
Keywords: ascites; cirrhosis; portal hypertension.
© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
References
REFERENCES
-
- European Association for the Study of the Liver. Electronic address eee, European Association for the Study of the L. EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis. J Hepatol. 2018;69(2):406-460.
-
- D'Amico G, Pasta L, Morabito A, et al. Competing risks and prognostic stages of cirrhosis: a 25-year inception cohort study of 494 patients. Aliment Pharmacol Ther. 2014;39(10):1180-1193.
-
- Fortune B, Cardenas A. Ascites, refractory ascites and hyponatremia in cirrhosis. Gastroenterol Rep. 2017;5(2):104-112.
-
- Caraceni P, Riggio O, Angeli P, et al. Long-term albumin administration in decompensated cirrhosis (ANSWER): an open-label randomised trial. Lancet. 2018;391(10138):2417-2429.
-
- Sola E, Sole C, Simon-Talero M, et al. Midodrine and albumin for prevention of complications in patients with cirrhosis awaiting liver transplantation. A randomized placebo-controlled trial. J Hepatol. 2018;69(6):1250-1259.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical