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Case Reports
. 2020 Apr;49(3):497-498.
doi: 10.1007/s11239-020-02067-x.

Clinical worsening despite intravenous thrombolysis in acute ischemic stroke secondary to carotid plaque rupture

Fabrizio Sallustio  1   2 , Domenico Samà  3 , Alfredo Paolo Mascolo  3 , Federico Marrama  3 , Mauro Fresilli  4 , Marina Diomedi  3
Affiliations
Case Reports

Clinical worsening despite intravenous thrombolysis in acute ischemic stroke secondary to carotid plaque rupture

Fabrizio Sallustio et al. J Thromb Thrombolysis. 2020 Apr.

Abstract

First-line therapy of acute ischemic stroke is intravenous thrombolysis (IVT) irrespective of etiology. We report on a patient with acute ischemic stroke secondary to carotid plaque rupture who experienced plaque thrombosis and marked clinical worsening despite IVT. While the latter is the gold standard therapy optimal platelets inhibition should be guaranteed to allow a safe as possible carotid intervention. Hereby we discuss all available strategies to be considered in order to better individualized treatment decision-making.

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References

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