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. 2020 Feb 19;105(4):591-593.
doi: 10.1016/j.neuron.2020.01.024.

Not Fade Away: Mechanisms of Neuronal ATP Homeostasis

Graeme W Davis  1
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Not Fade Away: Mechanisms of Neuronal ATP Homeostasis

Graeme W Davis. Neuron. .
Free article

Abstract

In this issue of Neuron, Ashrafi et al. (2020) identify a feedforward signaling mechanism that couples neuronal activity to the homeostatic maintenance of axonal and synaptic ATP production. This mechanism is achieved via changes in cytoplasmic calcium and activation of brain-specific, mitochondrial MICU3.

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