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. 2020 Feb 17;11(2):204.
doi: 10.3390/genes11020204.

Food and Non-Food-Related Behavior across Settings in Children with Prader-Willi Syndrome

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Food and Non-Food-Related Behavior across Settings in Children with Prader-Willi Syndrome

Marie G Gantz et al. Genes (Basel). .

Abstract

This study sought to describe food- and non-food-related behaviors of children aged 3 to 18 years with Prader-Willi syndrome (PWS) in home and school settings, as assessed by 86 parents and 63 teachers using 7 subscales of the Global Assessment of Individual's Behavior (GAIB). General Behavior Problem, Non-Food-Related Behavior Problem, and Non-Food-Related Obsessive Speech and Compulsive Behavior (OS/CB) scores did not differ significantly between parent and teacher reports. Food-Related Behavior Problem scores were higher in parent versus teacher reports when the mother had less than a college education (difference of 13.6 points, 95% Confidence Interval (CI) 5.1 to 22). Parents assigned higher Food-Related OS/CB scores than teachers (difference of 5.7 points, 95% CI 2.4 to 9.0). Although teachers reported fewer Food-Related OS/CB, they scored overall OS/CB higher for interfering with daily activities compared with parents (difference of 0.9 points, 95% CI 0.4 to 1.4). Understanding how behaviors manifest in home and school settings, and how they vary with socio-demographic and patient characteristics can help inform strategies to reduce behavior problems and improve outcomes.

Keywords: Prader–Willi syndrome; childhood; food-related behavior.

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Conflict of interest statement

The authors declare no conflict of interest. The funders supported the recruitment of participants, but were not involved in the design, of the study, data collection or analysis or preparation of the manuscript.

References

    1. Bittel D.C., Butler M.G. Prader–Willi syndrome: Clinical genetics, cytogenetics and molecular biology. Expert Rev. Mol. Med. 2005;7:1–20. doi: 10.1017/S1462399405009531. - DOI - PMC - PubMed
    1. Butler M.G., Manzardo A.M., Forster J.L. Prader-Willi Syndrome: Clinical Genetics and Diagnostic Aspects with Treatment Approaches. Curr. Pediatr. Rev. 2016;12:136–166. doi: 10.2174/1573396312666151123115250. - DOI - PMC - PubMed
    1. Ledbetter D.H., Riccardi V.M., Airhart S.D., Strobel R.J., Keenan B.S., Crawford J.D. Deletions of chromosome 15 as a cause of the Prader-Willi syndrome. N. Engl. J. Med. 1981;304:325–329. doi: 10.1056/NEJM198102053040604. - DOI - PubMed
    1. Butler M.G., Fischer W., Kibiryeva N., Bittel D.C. Array comparative genomic hybridization (aCGH) analysis in Prader-Willi syndrome. Am. J. Med. Genet. A. 2008;146:854–860. doi: 10.1002/ajmg.a.32249. - DOI - PMC - PubMed
    1. Cassidy S.B., Schwartz S., Miller J.L., Driscoll D.J. Prader-Willi syndrome. Genet. Med. 2012;14:10–26. doi: 10.1038/gim.0b013e31822bead0. - DOI - PubMed

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