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Practice Guideline
. 2020 Mar;271(3):e21-e93.
doi: 10.1097/SLA.0000000000003580.

The American Association of Endocrine Surgeons Guidelines for the Definitive Surgical Management of Thyroid Disease in Adults

Kepal N Patel  1 , Linwah Yip  2 , Carrie C Lubitz  3 , Elizabeth G Grubbs  4 , Barbra S Miller  5 , Wen Shen  6 , Peter Angelos  7 , Herbert Chen  8 , Gerard M Doherty  9 , Thomas J Fahey 3rd  10 , Electron Kebebew  11 , Virginia A Livolsi  12 , Nancy D Perrier  4 , Jennifer A Sipos  13 , Julie A Sosa  6 , David Steward  14 , Ralph P Tufano  15 , Christopher R McHenry  16 , Sally E Carty  2
Affiliations
Practice Guideline

The American Association of Endocrine Surgeons Guidelines for the Definitive Surgical Management of Thyroid Disease in Adults

Kepal N Patel et al. Ann Surg. 2020 Mar.

Abstract

Objective: To develop evidence-based recommendations for safe, effective, and appropriate thyroidectomy.

Background: Surgical management of thyroid disease has evolved considerably over several decades leading to variability in rendered care. Over 100,000 thyroid operations are performed annually in the US.

Methods: The medical literature from 1/1/1985 to 11/9/2018 was reviewed by a panel of 19 experts in thyroid disorders representing multiple disciplines. The authors used the best available evidence to construct surgical management recommendations. Levels of evidence were determined using the American College of Physicians grading system, and management recommendations were discussed to consensus. Members of the American Association of Endocrine Surgeons reviewed and commented on preliminary drafts of the content.

Results: These clinical guidelines analyze the indications for thyroidectomy as well as its definitions, technique, morbidity, and outcomes. Specific topics include Pathogenesis and Epidemiology, Initial Evaluation, Imaging, Fine Needle Aspiration Biopsy Diagnosis, Molecular Testing, Indications, Extent and Outcomes of Surgery, Preoperative Care, Initial Thyroidectomy, Perioperative Tissue Diagnosis, Nodal Dissection, Concurrent Parathyroidectomy, Hyperthyroid Conditions, Goiter, Adjuncts and Approaches to Thyroidectomy, Laryngology, Familial Thyroid Cancer, Postoperative Care and Complications, Cancer Management, and Reoperation.

Conclusions: Evidence-based guidelines were created to assist clinicians in the optimal surgical management of thyroid disease.

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References

    1. Sun GH, DeMonner S, Davis MM. Epidemiological and economic trends in inpatient and outpatient thyroidectomy in the United States, 1996–2006. Thyroid 2013; 23:727–733.
    1. Rubio GA, Koru-Sengal T, Vaghaiwalla TM, Parikh PP, Farra JC, Lew JI. Postoperative outcomes in Graves’ disease patients: results from the nationwide inpatient sample database. Thyroid 2017; 27:825–831.
    1. Haugen BRM, Alexander EK, Bible KC, et al. 2015 American Thyroid Association Management Guidelines for adult patients with thyroid nodules and differentiated thyroid cancer. Thyroid 2016; 26:1–133.
    1. Gharib H, Papini E, Paschke R, et al. American Association of Clinical Endocrinologists, Associazione Medici Endocrinologi, and European Thyroid Association Medical guidelines for clinical practice for the diagnosis and management of thyroid nodules: executive summary of recommendations. J Endocrinol Invest 2010; 33: (5 suppl): 51–56.
    1. Gharib H, Zeiger MA, Zini M, et al. AACE/AME Task Force on Thyroid Nodules. American Association of Clinical Endocrinologists and Associazione Medici Endocrinologi medical guidelines for clinical practice for the diagnosis and management of thyroid nodules. Endocr Pract 2006; 12:63–102.

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