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Case Reports
. 2018 Apr 30;26(2):320-323.
doi: 10.5606/tgkdc.dergisi.2018.14650. eCollection 2018 Apr.

An interesting mediastinal cyst case: Benign cystic mesothelioma

Fazlı Yanık  1 , Yekta Altemur Karamustafaoğlu  1 , Fulya Özpuyan  2 , Yener Yörük  1
Affiliations
Case Reports

An interesting mediastinal cyst case: Benign cystic mesothelioma

Fazlı Yanık et al. Turk Gogus Kalp Damar Cerrahisi Derg. .

Abstract

Anterior mediastinal, well-defined, ametabolic cystic lesion was detected incidentally in a 69-year-old male patient. Uniportal videothoracoscopic surgery was performed to the lesion for diagnosis and treatment purposes. Histopathological findings were in accordance with "benign cystic mesothelioma". Benign cystic mesothelioma has been defined in the abdomen, particularly among females of reproductive age. Benign cystic mesothelioma originating from mediastinal pleura is very rare entity and was not defined in the literature. To our knowledge, we present this rare and interesting mediastinal cystic lesion for the first time in the literature.

Keywords: Benign cystic mesothelioma; cyst; mediastinum.

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Conflict of interest statement

Conflict of Interest: The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Figures

Figure 1
Figure 1. (a) Anterior mediastinal, well-defined cystic lesion on axial chest/computed tomography images, marked with arrow. (b) Anterior mediastinal, well-defined ametabolic cystic lesion on axial positron emission tomography/computed tomography images, marked with arrow. (c) Macroscopic view of cystic lesion excised from anterior mediastinum. (d) Incision image of case operated with uniportal video-thoracoscopic surgery.
Figure 2
Figure 2. (a) Cyst wall and papillary proliferations of mesothelial cells. Cyst was lined with flatted benign epithelium (H-Ex4). (b) Immunohistochemically, proliferating mesothelial cells were positive for cytokeratin 7 and Hector Battifora mesothelial-1. Histiocytes were positive for cluster of differentiation 68. Ki-67 proliferation index was low (cytokeratin 7 immunohistochemistry x4; Hector Battifora mesothelial-1 immunohistochemistry x4; cluster of differentiation 68 immunohistochemistry x10; Ki-67 immunohistochemistry x10). (c) High-power view of lesion. Wilms tumor protein and calretinin reactivity on mesothelial cells (H-Ex10; Wilms tumor protein immunohistochemistry x10; calretinin immunohistochemistry x10).
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