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. 2020 Feb 6:7:2374289520903438.
doi: 10.1177/2374289520903438. eCollection 2020 Jan-Dec.

Educational Case: Infectious Esophagitis

Tara Narasimhalu  1 , Kristin A Olson  1
Affiliations

Educational Case: Infectious Esophagitis

Tara Narasimhalu et al. Acad Pathol. .

Abstract

The following fictional case is intended as a learning tool within the Pathology Competencies for Medical Education (PCME), a set of national standards for teaching pathology. These are divided into three basic competencies: Disease Mechanisms and Processes, Organ System Pathology, and Diagnostic Medicine and Therapeutic Pathology. For additional information, and a full list of learning objectives for all three competencies, see http://journals.sagepub.com/doi/10.1177/2374289517715040.1.

Keywords: Herpes simplex virus esophagitis; candida esophagitis; cytomegalovirus esophagitis; dysphagia; gastrointestinal tract; infectious esophagitis; mechanical disorders of bowel; organ system pathology; pathology competencies.

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Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Candida esophagitis with yeast forms amidst the “shredded wheat” like appearance of squamous epithelium (hematoxylin and eosin, ×40. Bar = 50 μm.).
Figure 2.
Figure 2.
Candida esophagitis with an abundance of pseudohyphae and yeast amidst squamous cells, arrow pointing toward the yeast forms (Gomori Methenamine-Silver, ×40. Bar = 60 μm.).
Figure 3.
Figure 3.
Herpes simplex virus esophagitis with infected squamous cells demonstrating multinucleation, nuclear molding, and chromatin margination (hematoxylin and eosin, ×40. Bar = 60 μm.).
Figure 4.
Figure 4.
Herpes simplex virus esophagitis with nuclear and cytoplasmic staining, confirming infection within cells (Immunohistochemical, ×40. Bar = 50 μm.).
Figure 5.
Figure 5.
Cytomegalovirus esophagitis with enlarged mesenchymal cells containing basophilic nuclei and pale perinuclear regions. Arrows pointing to “owl’s eye” appearance of cells (hematoxylin and eosin, ×40. Bar = 50 μm).
Figure 6.
Figure 6.
Cytomegalovirus esophagitis with nuclear staining, confirming infection within cells (immunohistochemical, ×40. Bar = 50 μm).
See this image and copyright information in PMC

References

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