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Multicenter Study
. 2020 May;17(5):646-650.
doi: 10.1513/AnnalsATS.201905-407RL.

Evaluation of QuantiFERON-TB Gold Plus for Predicting Incident Tuberculosis among Recent Contacts: A Prospective Cohort Study

Rishi K Gupta  1 , Heinke Kunst  2 , Marc Lipman  1   3 , Mahdad Noursadeghi  1 , Charlotte Jackson  1 , Jo Southern  4 , Ambreen Imran  1 , Stefan Lozewicz  5 , Ibrahim Abubakar  1
Affiliations
Multicenter Study

Evaluation of QuantiFERON-TB Gold Plus for Predicting Incident Tuberculosis among Recent Contacts: A Prospective Cohort Study

Rishi K Gupta et al. Ann Am Thorac Soc. 2020 May.
No abstract available

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Figures

Figure 1.
Figure 1.
(A) Receiver operating characteristic curves showing the performance of QuantiFERON-TB Gold Plus for predicting incident tuberculosis during the duration of follow-up, stratified by antigen tube interferon-γ responses. TB max = higher of the CD4+-response tube (TB1) and CD8+-response tube (TB2). AUC = area under the curve (95% confidence interval). (B) Scatterplot showing association of interferon-γ responses in the TB1 and TB2 tubes.
See this image and copyright information in PMC

References

    1. World Health Organization. Latent TB infection: updated and consolidated guidelines for programmatic management. Geneva: WHO; 2018 [accessed 2018 Aug 15]. Available from: http://www.who.int/tb/publications/2018/latent-tuberculosis-infection/en/
    1. Pai M, Denkinger CM, Kik SV, Rangaka MX, Zwerling A, Oxlade O, et al. Gamma interferon release assays for detection of Mycobacterium tuberculosis infection. Clin Microbiol Rev. 2014;27:3–20. - PMC - PubMed
    1. Zellweger JP, Sotgiu G, Block M, Dore S, Altet N, Blunschi R, et al. TBNET. Risk assessment of tuberculosis in contacts by IFN-γ release assays. A Tuberculosis Network European Trials Group study. Am J Respir Crit Care Med. 2015;191:1176–1184. - PubMed
    1. Sloot R, Schim van der Loeff MF, Kouw PM, Borgdorff MW. Risk of tuberculosis after recent exposure. A 10-year follow-up study of contacts in Amsterdam. Am J Respir Crit Care Med. 2014;190:1044–1052. - PubMed
    1. Haldar P, Thuraisingam H, Patel H, Pereira N, Free RC, Entwisle J, et al. Single-step QuantiFERON screening of adult contacts: a prospective cohort study of tuberculosis risk. Thorax. 2013;68:240–246. - PubMed

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