[Induction of the antileukemic activity in nonimmune allogeneic splenocytes using spleen hemoregulators]
[Article in
Russian]
- PMID: 3208692
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[Induction of the antileukemic activity in nonimmune allogeneic splenocytes using spleen hemoregulators]
[Article in
Russian]
Eksp Onkol.
1988.
Abstract
The leukemic mice treated with cyclophosphamide were injected twice a week with the allogenic splenocytes treated for 4 h with the substance isolated from the calf spleen. The leukemia growth inhibition was observed. Syngenic splenocytes were inactive. Allogenic but not syngenic splenocytes manifested a certain antileukemic activity observed in the Winn neutralization and 51Cr release tests, however this activity did not correlate quantitatively with more pronounced antileukemic action of cells in vivo.
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