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. 1988;10(5):57-61.

[Induction of the antileukemic activity in nonimmune allogeneic splenocytes using spleen hemoregulators]

[Article in Russian]
A I Svirnovskiĭ, T V Shimanskaia, A V Bakun, V M Ageĭchik
  • PMID: 3208692

[Induction of the antileukemic activity in nonimmune allogeneic splenocytes using spleen hemoregulators]

[Article in Russian]
A I Svirnovskiĭ et al. Eksp Onkol. 1988.

Abstract

The leukemic mice treated with cyclophosphamide were injected twice a week with the allogenic splenocytes treated for 4 h with the substance isolated from the calf spleen. The leukemia growth inhibition was observed. Syngenic splenocytes were inactive. Allogenic but not syngenic splenocytes manifested a certain antileukemic activity observed in the Winn neutralization and 51Cr release tests, however this activity did not correlate quantitatively with more pronounced antileukemic action of cells in vivo.

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