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Review
. 2021 Apr;31(3):172-176.
doi: 10.1016/j.tcm.2020.01.008. Epub 2020 Feb 6.

Do peak times exist for sudden cardiac arrest?

Archana Ramireddy  1 , Sumeet S Chugh  2
Affiliations
Review

Do peak times exist for sudden cardiac arrest?

Archana Ramireddy et al. Trends Cardiovasc Med. 2021 Apr.

Abstract

Sudden cardiac arrest remains an unexpected and dynamic cardiovascular disease process that continues to present challenges for accurate risk prediction and prevention. The notion of a circadian pattern in the occurrence of sudden cardiac arrest had long been supported by the presence of an early morning peak; however, more recent studies are calling this observation into question. This likely paradigm shift in the presentation and mechanisms of sudden cardiac arrest has major implications and needs to be carefully considered. In this review, we present the current state of the science of circadian and septadian trends in sudden cardiac arrest through an in-depth analysis of the published literature.

Keywords: Sudden cardiac arrest; circadian rhythm.

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Conflict of interest statement

Conflicts of Interest

AR: none

SSC: none

Figures

Figure 1:
Figure 1:
The implications of a loss of the circadian variation in sudden cardiac arrest.
Figure 2:
Figure 2:
Circadian and septadian patterns in sudden cardiac arrest as evaluated by proportions of events occurring during 2-hour intervals and on each day of the week. The expected SCA peak during the morning hours and on Mondays was absent. A new nadir was seen on Sunday. There were no significant differences in the subgroup of SCA events witnessed by bystanders or emergency medical response personnel compared to the overall SCA events. SCA = sudden cardiac arrest. (Modified from Ni et al. Shift in sudden cardiac arrest. Heart Rhythm. 2019)
Figure 3:
Figure 3:
Proportions of sudden cardiac arrest occurrence in specific subgroups of individuals based on time of day. (Modified from Ni et al. Shift in sudden cardiac arrest. Heart Rhythm. 2019)
See this image and copyright information in PMC

Comment in

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