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Review
. 2020:87:179-203.
doi: 10.1016/bs.apha.2019.10.004. Epub 2020 Jan 13.

Pharmacological effects of icariin

Chunyang He  1 , Ze Wang  2 , Jingshan Shi  3
Affiliations
Review

Pharmacological effects of icariin

Chunyang He et al. Adv Pharmacol. 2020.

Abstract

Icariin (ICA) is a principal active component from traditional Chinese medicine Epimedium grandiflorum. To explain its traditional medical usages by modern science, a variety of pharmacological effects have been studied for ICA. In this review, we summarized the pharmacokinetics of ICA as well as its pharmacological mechanisms in neurodegenerative disease, cardiovascular disease, anti-osteoporosis, anti-inflammation, anti-oxidative stress, anti-depression and anti-tumors.

Keywords: Cardiovascular disease; Icariin; Neurodegenerative disease; Pharmacokinetics; Pharmacology; Traditional Chinese medicine.

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Conflict of interest statement

Conflict of interest The authors confirm that this article content has no conflict of interest.

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