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. 2019 Nov 19;7(2):556-562.
doi: 10.1002/nop2.420. eCollection 2020 Mar.

Health-related quality of life in patients with heart failure eligible for treatment with sacubitril-valsartan

Lena Holmlund  1 , Margareta Brännström  1 , Krister Lindmark  2 , Camilla Sandberg  2 , Karin Hellström Ängerud  1
Affiliations

Health-related quality of life in patients with heart failure eligible for treatment with sacubitril-valsartan

Lena Holmlund et al. Nurs Open. .

Abstract

Aim: To describe and compare self-reported health-related quality of life between younger and older patients with severe heart failure eligible for treatment with sacubitril-valsartan and to explore the association between health-related quality of life and age, NYHA classification, systolic blood pressure and NT-proBNP level.

Design: Cross-sectional study.

Methods: A total of 59 patients, eligible for treatment with sacubitril-valsartan were consecutively included and divided into a younger (≤75 years) and older group (>75 years). Health-related quality of life was assessed using the Kansas City Cardiomyopathy Questionnaire and the EuroQol 5-dimensions. Data were collected between June 2016 and January 2018. The STROBE checklist was used.

Results: There were no differences in overall health-related quality of life between the age groups. The older patients reported lower scores in two domains measured with the Kansas City Cardiomyopathy Questionnaire, namely self-efficacy (67.0 SD 22.1 vs. 78.8 SD 19.7) and physical limitation (75.6 SD 19.0 vs. 86.3 SD 14.4). Higher NYHA class was independently associated with lower Kansas City Cardiomyopathy Questionnaire Overall Summary Score.

Keywords: health‐related quality of life; heart failure; self‐care; self‐efficacy.

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Conflict of interest statement

KL has received lecture grants from Novartis. For the remaining authors, none were declared.

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