Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Multicenter Study

Human Exposure to Hantaviruses Associated with Rodents of the Murinae Subfamily, Madagascar

Harinirina Aina Rabemananjara et al. Emerg Infect Dis. 2020 Mar.

Abstract

We conducted a national human serologic study of a hantavirus detected in Madagascar rodents using a commercial kit and a new ELISA targeting the virus. Our results suggest a conservative estimate of 2.7% (46/1,680) IgG seroprevalence. A second single-district study using the new ELISA revealed a higher prevalence (7.2%; 10/139).

Keywords: Madagascar; Murinae; hantavirus; human population; rodents; seroprevalence; viruses; zoonoses.

PubMed Disclaimer

Figures

Figure
Figure
Geographic distribution of IgG hantavirus human seroprevalence in Madagascar for the 28 sites of the national-scale study and (inset) for the 4 sites close to forest in Moramanga district. Maps were built with QGIS software version 3.8.0—Zanzibar (Open Source Geospatial Foundation Project, http://qgis.osgeo.org). Small inset map shows location of Madagascar off the coast of Africa.
See this image and copyright information in PMC

References

    1. Jonsson CB, Figueiredo LT, Vapalahti O. A global perspective on hantavirus ecology, epidemiology, and disease. Clin Microbiol Rev. 2010;23:412–41. 10.1128/CMR.00062-09 - DOI - PMC - PubMed
    1. Vaheri A, Strandin T, Hepojoki J, Sironen T, Henttonen H, Mäkelä S, et al. Uncovering the mysteries of hantavirus infections. Nat Rev Microbiol. 2013;11:539–50. 10.1038/nrmicro3066 - DOI - PubMed
    1. Muranyi W, Bahr U, Zeier M, van der Woude FJ. Hantavirus infection. J Am Soc Nephrol. 2005;16:3669–79. 10.1681/ASN.2005050561 - DOI - PubMed
    1. Witkowski PT, Klempa B, Ithete NL, Auste B, Mfune JKE, Hoveka J, et al. Hantaviruses in Africa. Virus Res. 2014;187:34–42. 10.1016/j.virusres.2013.12.039 - DOI - PubMed
    1. Reynes JM, Razafindralambo NK, Lacoste V, Olive MM, Barivelo TA, Soarimalala V, et al. Anjozorobe hantavirus, a new genetic variant of Thailand virus detected in rodents from Madagascar. Vector Borne Zoonotic Dis. 2014;14:212–9. 10.1089/vbz.2013.1359 - DOI - PMC - PubMed

Publication types