Sections

• Preface
• Acknowledgment
• Abbreviations
• Contributors
• About the Editors
• I. Introduction Topic leaders: Mohamad Mohty and Jane Apperley
  • 1. HSCT: Historical Perspective
  • 2. The EBMT: History, Present, and Future
  • 3. The Role of Unrelated Donor Registries in HSCT
  • 4. The HSCT Unit
  • 5. JACIE Accreditation of HSCT Programs
  • 6. Statistical Methods in HSCT and Cellular Therapies
• II. Biological Aspects Topic leaders: Chiara Bonini and Jürgen Kuball
  • 7. Biological Properties of HSC: Scientific Basis for HSCT
  • 8. Biological Properties of Cells Other Than HSCs
  • 9. Histocompatibility
  • 10. Clinical and Biological Concepts for Mastering Immune Reconstitution After HSCT: Toward Practical Guidelines and Greater Harmonization
• III. Methodology and Clinical Aspects Topic leaders: Arnon Nagler and Nicolaus Kröger
  • 11. Evaluation and Counseling of Candidates
  • 12. Donor Selection for Adults and Pediatrics
  • 13. Conditioning
  • 14. Bone Marrow Harvesting for HSCT
  • 15. Mobilization and Collection of HSC
  • 16. Collection of HSC in Children
  • 17. Processing, Cryopreserving and Controlling the Quality of HSCs
  • 18. Procurement and Management of Cord Blood
  • 19. Graft Manipulation
  • 20. Documentation of Engraftment and Chimerism After HSCT
  • 21. Short- and Long-Term Controls After HSCT
• IV. General Management of the Patient Topic leaders: Carlo Dufour, Silvia Montoto and John Murray
  • 22. Vascular Access
  • 23. Transfusion Support
  • 24. Nutritional Support
  • 25. GVHD Prophylaxis (Immunosuppression)
  • 26. Management ATG (SIRS)
  • 27. Infection Control and Isolation Procedures
  • 28. General Management of the Patient: Specific Aspects of Children
  • 29. Vaccinations
  • 30. Psychological Morbidity and Support
  • 31. Clinically Relevant Drug Interactions in HSCT
  • 32. Role of Nursing in HSCT
  • 33. Ethical Issues in HSCT
  • 34. Quality of Life Assessment After HSCT for Pediatric and Adults
• V. HSCT Complications and Management Topic leaders: Jan Styczynski, Enric Carreras and Per Ljungman
  • 35. Neutropenic Fever
  • 36. Bacterial Infections
  • 37. Invasive Fungal Infections
  • 38. Viral Infections
  • 39. Other Life-Threatening Infections
  • 40. Bleeding and Thrombotic Complications
  • 41. Graft Failure
  • 42. Early Complications of Endothelial Origin
  • 43. Acute Graft-Versus-Host Disease
  • 44. Chronic Graft-Versus-Host Disease
  • 45. Post transplant Lymphoproliferative Syndromes
  • 46. Iron Overload
  • 47. Secondary Neoplasia (Other than PTLPS)
• VI. Specific Organ Complications Topic leaders: Grzegorz Basak and John Snowden
  • 48. Ocular and Oral Complications
  • 49. Hepatic Complications
  • 50. Gastrointestinal Complications
  • 51. Haemorrhagic Cystitis and Renal Dysfunction
  • 52. Noninfectious Pulmonary Complications
  • 53. Neurological Complications
  • 54. Skin, Hair and Musculoskeletal Complications
  • 55. Cardiovascular Diseases and Metabolic Syndrome
  • 56. Endocrine Disorders, Fertility and Sexual Health
• VII. Prevention and Management of Relapse Topic leaders: Peter Bader and Nicolaus Kröger
  • 57. Monitoring Minimal Residual Disease in ALL and AML
  • 58. Prevention and Treatment of Relapse by Drugs
  • 59. Delayed Transfer of Immune Cells or the Art of Donor Lymphocyte Infusion
  • 60. Cellular Therapy with Engineered T Cells, Efficacy and Side Effects
  • 61. Mechanisms of Immune Resistance
  • 62. Regulatory Aspects of ATMP Versus Minimally Manipulated Immune Cells
• VIII. Specific Modalities of HSCT and Management Topic leaders: Andrew Gennery, Anna Sureda and Arjan Lankester
  • 63. At-Home HSCT
  • 64. Umbilical Cord Blood Transplantation in Children and Adults
  • 65. Haploidentical HSCT
  • 66. Photopheresis in Adults and Pediatrics
  • 67. Overweight and Obese Patients
  • 68. HSCT in Elderly Patients
• IX. Indications and Results Topic leaders: Rafael Duarte and Nicolaus Kröger
  • 69. Acute Myeloid Leukemia in Adults
  • 70. Acute Myeloid Leukemia in Children
  • 71. Acute Lymphoblastic Leukemia in Adults
  • 72. Acute Lymphoblastic Leukemia in Children and Adolescents
  • 73. Myelodysplastic Syndromes
  • 74. Pediatric MDS Including Refractory Cytopenia and Juvenile Myelomonocytic Leukemia
  • 75. Myelodysplastic/Myeloproliferative Neoplasms
  • 76. Myeloproliferative Neoplasms
  • 77. Severe Aplastic Anemia and PNH
  • 78. Fanconi’s Anemia and Other Hereditary Bone Marrow Failure Syndromes
  • 79. Hemoglobinopathies (Sickle Cell Disease and Thalassemia)
  • 80. Multiple Myeloma
  • 81. Systemic Light Chain Amyloidosis
  • 82. POEMS Syndrome and Disease Produced by Other Monoclonal Immunoglobulins
  • 83. Follicular Lymphoma
  • 84. Chronic Lymphocytic Leukemia
  • 85. Diffuse Large B-Cell Lymphoma
  • 86. Mantle Cell Lymphoma
  • 87. Other T- and B-Aggressive Lymphomas and Lymphomas Associated with HIV
  • 88. Classical Hodgkin’s Lymphoma
  • 89. Primary Immunodeficiencies
  • 90. Inborn Errors of Metabolism and Osteopetrosis
  • 91. Autoimmune Disease
  • 92. Solid Tumours
• Appendix: EBMT Registry