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Review

Mycobacterium ulcerans Infection in French Guiana; Current State of Knowledge

Pierre Couppié  1   2 , Romain Blaizot  1   2 , Camilla J. Velvin  3 , Maylis Douine  2   4 , Marine Combe  3 , Mathieu Nacher  2   4 , Rodolphe E. Gozlan  3
Gerd Pluschke  1 , Katharina Röltgen  2
, editors.
In: Buruli Ulcer: Mycobacterium Ulcerans Disease [Internet]. Cham (CH): Springer; 2019.
.
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Review

Mycobacterium ulcerans Infection in French Guiana; Current State of Knowledge

Pierre Couppié et al.
Free Books & Documents

Excerpt

M. ulcerans infections (Buruli ulcer; BU) have been reported in French Guiana since the 1960s [1]. It is striking to see that French Guiana concentrates most of the cases of BU in America with only a few cases reported in Suriname, Peru, Mexico and Bolivia in the past [2, 3]. Either BU is underdiagnosed and underreported in most of the continent; or the specific environmental conditions in French Guiana represent a unique niche for the disease to appear; or a sublineage of M. ulcerans has established in French Guiana that has a higher virulence than other members of the ancestral lineage found in the Americas.

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References

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    1. Elguero E, Broutin H, Nacher M, Chevillon C, Guegan JF, Couppié P (2009) Environment risk factors of Buruli ulcer. A case-control study in French Guiana. In: Second International Conference on Buruli Ulcer, Cotonou, Benin, March 30–April 3, 2009
    1. Sambourg E, Dufour J, Edouard S, Morris A, Mosnier E, Reynaud Y, Sainte-Marie D, Nacher M, Guégan JF, Couppié P (2014) Réponses et réactions paradoxales au cours du traitement médicamenteux de l’infection à Mycobacterium ulcerans (ulcère de Buruli). Quatre observations en Guyane française. Ann Dermatol Venereol 141:413–418 - PubMed

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