Conditioning
- PMID: 32091747
- Bookshelf ID: NBK553926
- DOI: 10.1007/978-3-030-02278-5_13
Conditioning
Excerpt
HSCT is a therapeutic procedure that can cure and/or prolong life in a broad range of hematologic disorders including malignant and nonmalignant pathologies. Conditioning is the preparative regimen that is administered to the patients undergoing HSCT before the infusion of the stem cell grafts.
Copyright 2019, EBMT and the Author(s).
Sections
- 13.1. Overview
- 13.2. Total Body Irradiation
- 13.3. Myeloablative Non-TBI-Containing Conditioning
- 13.4. Nonmyeloablative, Reduced Intensity and Reduced Toxicity Conditioning
- 13.5. Conditioning Regimens for Allo-HSCT from Alternative Donors: MMUD, CB, and Haploidentical
- 13.6. Preparative Conditioning for Autologous HSCT
- References
References
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- Aoudjhane M, Labopin M, Gorin NC, et al. Comparative outcome of reduced intensity and myeloablative conditioning regimen in HLA identical sibling allogeneic haematopoietic stem cell transplantation for patients older than 50 years of age with acute myeloblastic leukaemia: a retrospective survey from the Acute Leukemia Working Party (ALWP) of the European Group for Blood and Marrow Transplantation (EBMT). Leukemia. 2005;19:2304–12. - PubMed
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- Baron F, Mohty M, Blaise D, et al. Anti-thymocyte globulin as graft-versus-host disease prevention in the setting of allogeneic peripheral blood stem cell transplantation: a review from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation. Haematologica. 2017;102:224–34. - PMC - PubMed
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- Belkacemi Y, Labopin M, Giebel S, et al. Single dose daily fractionated is not Inferior to twice a day fractionated total body irradiation prior to allogeneic stem cell transplantation for acute leukemia: a useful practice simplification resulting from the Sarasin Study. Int J Radiat Oncol Biol Phys. 2018;102:515–26. - PubMed