Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review

Hemoglobinopathies (Sickle Cell Disease and Thalassemia)

Barbara Cappelli  1 , Eliane Gluckman  2 , Khaled Ghanem  3 , Miguel R. Abboud  4
Enric Carreras  1 , Carlo Dufour  2 , Mohamad Mohty  3 , Nicolaus Kröger  4
, editors.
In: The EBMT Handbook: Hematopoietic Stem Cell Transplantation and Cellular Therapies [Internet]. 7th edition. Cham (CH): Springer; 2019. Chapter 79.
Affiliations
Free Books & Documents
Review

Hemoglobinopathies (Sickle Cell Disease and Thalassemia)

Barbara Cappelli et al.
Free Books & Documents

Excerpt

Sickle cell disease (SCD) is the most common inherited hemoglobinopathy worldwide.

PubMed Disclaimer

References

    1. Andreani M, Nesci S, Lucarelli G, et al. Long-term survival of ex-thalassemic patients with persistent mixed chimerism after bone marrow transplantation. Bone Marrow Transplant. 2000;25:401–4. - PubMed
    1. Angelucci E, Matthes-Martin S, Baronciani D, et al. EBMT Inborn Error and EBMT Paediatric Working Parties. Hematopoietic stem cell transplantation in thalassemia major and sickle cell disease: indications and management recommendations from an international expert panel. Haematologica. 2014;99:811–20. - PMC - PubMed
    1. Angelucci E, Pilo F, Coates TD. Transplantation in thalassemia: Revisiting the Pesaro risk factors 25 years later. Am J Hematol. 2017;92:411–3. - PubMed
    1. Arnold SD, Bhatia M, Horan J, Krishnamurti L. Haematopoietic stem cell transplantation for sickle cell disease - current practice and new approaches. Br J Haematol. 2016;174:515–25. - PubMed
    1. Baronciani D, Angelucci E, Potschger U, et al. Hemopoietic stem cell transplantation in thalassemia: a report from the European Society for Blood and Bone Marrow Transplantation Hemoglobinopathy Registry, 2000-2010. Bone Marrow Transplant. 2016;51:536–41. - PubMed

LinkOut - more resources