Bone Marrow Harvesting for HSCT
- PMID: 32091775
- Bookshelf ID: NBK553958
- DOI: 10.1007/978-3-030-02278-5_14
Bone Marrow Harvesting for HSCT
Excerpt
Historically, the bone marrow (BM) has been the first source of stem cells considered since the early 1960s for HSCT (Santos ; Thomas et al. ; Mathe ; Gorin et al. 1990). Parallel attempts at using fetal liver cells at that time have remained unsuccessful. In 1986 the first success of an unrelated cord blood (UCB) transplantation in a child promoted UCB (Gluckman et al. 1997) as an alternative source in certain settings.
Copyright 2019, EBMT and the Author(s).
Sections
- 14.1. Introduction
- 14.2. Indications for Considering and Possibly Selecting BM as a Preferred Source of HSC
- 14.3. Mobilized or Primed Marrow
- 14.4. Technique of BM Collection and Impact of the Dose of Nucleated Cells Infused
- 14.5. Complications of Bone Marrow Collections
- 14.6. Bone Marrow Cryopreservation
- 14.7. Quality Control for BM Harvesting and Cryopreservation
- 14.8. Conclusions
- References
References
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- Aird W, Labopin M, Gorin NC, Antin JH. Long-term cryopreservation of human stem cells. Bone Marrow Transplant. 1992;9:487–90. - PubMed
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- Barone A, Lucarelli A, Onofrillo D, et al. Diagnosis and management of acquired aplastic anemia in childhood. Guidelines from the marrow failure study group of the pediatric haemato-oncology Italian association (AIEOP). Blood Cells Mol Dis. 2015;55:40–7. - PubMed
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- Bhella S, Navneet S, Majhail NS, Betcher J, et al. Choosing wisely BMT: American society for blood and marrow transplantation and Canadian blood and marrow transplant group’s list of 5 tests and treatments to question in blood and marrow transplantation. Biol Blood Marrow Transplant. 2018;24:909–13. - PubMed
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