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Review

Autoimmune Disease

Tobias Alexander  1 , Basil Sharrack  2 , Montserrat Rovira  3 , Dominique Farge  4   5 , John A. Snowden  6
Enric Carreras  1 , Carlo Dufour  2 , Mohamad Mohty  3 , Nicolaus Kröger  4
, editors.
In: The EBMT Handbook: Hematopoietic Stem Cell Transplantation and Cellular Therapies [Internet]. 7th edition. Cham (CH): Springer; 2019. Chapter 91.
Affiliations
Review

Autoimmune Disease

Tobias Alexander et al.

Excerpt

Autoimmune diseases (ADs) are a heterogeneous group of diseases affecting 8–10% of the Western population, which constitute a heavy burden to society and are often debilitating and disabling for affected individuals.

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References

    1. Alchi B, Jayne D, Labopin M, et al. Autologous haematopoietic stem cell transplantation for systemic lupus erythematosus: data from the European Group for Blood and Marrow Transplantation registry. Lupus. 2013;22:245–53. - PubMed
    1. Alexander T, Hiepe F. Autologous haematopoietic stem cell transplantation for systemic lupus erythematosus: time ready for a paradigm shift? Clin Exp Rheumatol. 2017;35:359–61. - PubMed
    1. Alexander T, Bondanza A, Muraro PA, et al. SCT for severe autoimmune diseases: consensus guidelines of the European Society for Blood and Marrow Transplantation for immune monitoring and biobanking. Bone Marrow Transplant. 2015;50:173–80. - PMC - PubMed
    1. Alexander T, Arnold R, Hiepe F, RAIDbruch A. Resetting the immune system with immunoablation and autologous haematopoietic stem cell transplantation in autoimmune diseases. Clin Exp Rheumatol. 2016;34:53–7. - PubMed
    1. Atkins HL, Bowman M, Allan D, et al. Immunoablation and autologous haemopoietic stem-cell transplantation for aggressive multiple sclerosis: a multicentre single-group phase 2 trial. Lancet. 2016;388:576–85. - PubMed