Delayed Transfer of Immune Cells or the Art of Donor Lymphocyte Infusion
- PMID: 32091816
- Bookshelf ID: NBK554008
- DOI: 10.1007/978-3-030-02278-5_59
Delayed Transfer of Immune Cells or the Art of Donor Lymphocyte Infusion
Excerpt
In the context of an allogeneic HSCT, the interplay between host and donor immune cells is considered to be the primary mechanism responsible for graft-versus-leukemia (GVL) reactivity and also able to mediate GVHD (Kolb et al.
Copyright 2019, EBMT and the Author(s).
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References
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- Admiraal R, Nierkens S, de Witte MA, et al. Association between anti-thymocyte globulin exposure and survival outcomes in adult unrelated haemopoietic cell transplantation: a multicentre, retrospective, pharmacodynamic cohort analysis. Lancet Haematol. 2017;4:e183–e91. - PubMed
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- Alyea EP, DeAngelo DJ, Moldrem J, et al. NCI First International Workshop on the Biology, Prevention and Treatment of Relapse after Allogeneic Hematopoietic Cell Transplantation: report from the committee on prevention of relapse following allogeneic cell transplantation for hematologic malignancies. Biol Blood Marrow Transplant. 2010;16:1037–69. - PMC - PubMed
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- Boelens JJ, Admiraal R, Kuball J, Nierkens S. Fine-tuning antithymocyte globulin dosing and harmonizing clinical trial design. J Clin Oncol. 2018;36:1175–6. - PubMed
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