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Comment
. 2020 Jun;80(6):671-693.
doi: 10.1016/j.jinf.2020.02.001. Epub 2020 Feb 22.

The continuous evolution and dissemination of 2019 novel human coronavirus

Jiahao Zhang  1 , Kaixiong Ma  1 , Huanan Li  1 , Ming Liao  2 , Wenbao Qi  3
Affiliations
Comment

The continuous evolution and dissemination of 2019 novel human coronavirus

Jiahao Zhang et al. J Infect. 2020 Jun.
No abstract available

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Conflict of interest statement

Declaration of Competing Interest All authors have no potential conflicts of interest to disclose.

Figures

Fig 1
Fig. 1
Geographic distribution of the 2019-nCoV and the number of human cases. Geographic distribution of the 2019-nCoV in(A)China and(B)the world, respectively. The color of bar chart represents the number of human infection. The blue star represents the location of Wuhan, China. Data are available from the World Health Organization (https://www.who.int) and National Health and Family Planning Commission of the People's Republic of China (http://www.nhfpc.gov.cn). The map in the inset indicates islands in the South China Sea. The map was designed using ArcGIS Desktop 10.4 software (http://www.esri.com/software/arcgis/arcgis-for-desktop/). (C) The number of human cases by date are plotted, which shows a gradual increase over time. The blue bar chart represents the numbers of confirmed cases, and the gray bar chart represents the death toll, and the yellow bar chart represents the numbers of recovered cases.
Fig 2
Fig. 2
Evolutionary history of the 2019-nCoV. (A) Structural analysis of envelope spike (S) protein of novel coronaviruses. The red and blue regions indicate the spike protein 1 and spike protein 2, respectively. The wathet blue region indicates the receptor binding region of 2019-nCoV. The correspondencing amino acids to the three-dimensional (3D) structure of the S protein were mapped using MacPymol (http://www.pymol.org/). (B) A simple model of 2019-nCoV origin inferred from phylogenic tree and clinical feature of humans infected with the 2019-nCoV. (C) Maximum likelihood tree of the full-length genome of coronaviruses using MEGA 7 version. Red color indicates the human-origin coronaviruses, and red dot represents the isolates in Wuhan, China. The scale bar represents the number of nucleotide substitutions per site (subs/site).
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