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. 2020 Jul:81:104260.
doi: 10.1016/j.meegid.2020.104260. Epub 2020 Feb 21.

Genetic diversity and evolution of SARS-CoV-2

Tung Phan  1
Affiliations

Genetic diversity and evolution of SARS-CoV-2

Tung Phan. Infect Genet Evol. 2020 Jul.

Abstract

COVID-19 is a viral respiratory illness caused by a new coronavirus called SARS-CoV-2. The World Health Organization declared the SARS-CoV-2 outbreak a global public health emergency. We performed genetic analyses of eighty-six complete or near-complete genomes of SARS-CoV-2 and revealed many mutations and deletions on coding and non-coding regions. These observations provided evidence of the genetic diversity and rapid evolution of this novel coronavirus.

Keywords: Coronavirus; Genomic diversity; Mutations; SARS-CoV-2.

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Conflict of interest statement

Declaration of Competing Interest The author declares no competing financial interests.

Figures

Fig. 1
Fig. 1
Genomic organization of SARS-CoV-2 and pairwise nucleotide sequence alignment showing deletions in the ORF1ab polyprotein and in the 3′ end of the genome.
See this image and copyright information in PMC

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