In severe liver disease, citrate can be used safely: the question remains-by which mechanism
- PMID: 32093726
- PMCID: PMC7038605
- DOI: 10.1186/s13054-020-2801-2
In severe liver disease, citrate can be used safely: the question remains-by which mechanism
Conflict of interest statement
The authors declare that they have no competing interests.
Comment on
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Safety and efficacy of regional citrate anticoagulation for continuous renal replacement therapy in liver failure patients: a systematic review and meta-analysis.Crit Care. 2019 Jan 24;23(1):22. doi: 10.1186/s13054-019-2317-9. Crit Care. 2019. PMID: 30678706 Free PMC article.
References
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- Khadzhynov D, Schelter C, Lieker I, Mika A, Staeck O, Neumayer HH, et al. Incidence and outcome of metabolic disarrangements consistent with citrate accumulation in critically ill patients undergoing continuous venovenous hemodialysis with regional citrate anticoagulation. J Crit Care. 2014;29(2):265–271. doi: 10.1016/j.jcrc.2013.10.015. - DOI - PubMed
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- Slowinski T, Morgera S, Joannidis M, Henneberg T, Stocker R, Helset E, et al. Safety and efficacy of regional citrate anticoagulation in continuous venovenous hemodialysis in the presence of liver failure: the liver citrate anticoagulation threshold (L-CAT) observational study. Crit Care. 2015;19:349. doi: 10.1186/s13054-015-1066-7. - DOI - PMC - PubMed
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