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. 2020 Apr:164:105914.
doi: 10.1016/j.rmed.2020.105914. Epub 2020 Feb 19.

Electronic medication monitors help determine adherence subgroups in asthma

Heather E H De Keyser  1 , Leanne Kaye  2 , William C Anderson  3 , Rahul Gondalia  4 , Ben Theye  5 , Stanley J Szefler  6 , David A Stempel  7
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Free article

Electronic medication monitors help determine adherence subgroups in asthma

Heather E H De Keyser et al. Respir Med. 2020 Apr.
Free article

Abstract

Non-adherence to treatment regimens in asthma is well described, however less is known about temporal patterns of medication use. We monitored 20 weeks of controller medication use and analyzed these patterns in patients ≥4 years of age with self-reported asthma enrolled in a digital health program. At baseline, approximately 20%, 28%, 25% and 27% of patients had optimal, moderate, sub-optimal and poor adherence, respectively. Medication adherence decreased in all groups in this study. The largest absolute decreases in adherence (-32%) were observed for moderately adherent patients. Certain adherence patterns which demonstrated greater declines, that, once identified, could be intervened upon.

Keywords: Adherence; Asthma; Electronic medication monitoring.

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Conflict of interest statement

Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Heather Hoch has served as a consultant to Astra Zeneca, and has received research support from Propeller Health, the Children’s Hospital Colorado Research Institute, and the Colorado Department of Public Health and Environment Cancer, Cardiovascular and Pulmonary Disease Program. William Anderson has served as a consultant to Astra Zeneca. Stanley Szefler has consulted for Astra Zeneca, Boehringer-Ingelheim, GlaxoSmithKline, Novartis, Propeller Health, Regeneron and Sanofi and has received research support from the National Institutes of Health, the National Heart, Lung and Blood Institute and the Colorado Department of Public Health and Environment Cancer, Cardiovascular and Pulmonary Disease Program. Leanne Kaye, Rahul Gondalia, Ben Theye, and David A. Stempel are employees of Propeller Health and receive compensation and stock ownership.

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