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. 2020 Feb 24;7(1):67.
doi: 10.1038/s41597-020-0401-2.

Fox Insight collects online, longitudinal patient-reported outcomes and genetic data on Parkinson's disease

Luba Smolensky  1 , Ninad Amondikar  2 , Karen Crawford  3 , Scott Neu  3 , Catherine M Kopil  2 , Margaret Daeschler  2 , Lindsey Riley  2 ; 23andMe Research Team; Ethan Brown  4 , Arthur W Toga  3 , Caroline Tanner  4
Collaborators, Affiliations

Fox Insight collects online, longitudinal patient-reported outcomes and genetic data on Parkinson's disease

Luba Smolensky et al. Sci Data. .

Abstract

Fox Insight is an online, longitudinal health study of people with and without Parkinson's disease with targeted enrollment set to at least 125,000 individuals. Fox Insight data is a rich data set facilitating discovery, validation, and reproducibility in Parkinson's disease research. The dataset is generated through routine longitudinal assessments (health and medical questionnaires evaluated at regular cycles), one-time questionnaires about environmental exposure and healthcare preferences, and genetic data collection. Qualified Researchers can explore, analyze, and download patient-reported outcomes (PROs) data and Parkinson's disease- related genetic variants at https://foxden.michaeljfox.org. The full Fox Insight genetic data set, including approximately 600,000 single nucleotide polymorphisms (SNPs), can be requested separately with institutional review and are described outside of this data descriptor.

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Conflict of interest statement

Several authors are current or former staff members at The Michael J. Fox Foundation for Parkinson’s Research, the sponsor of Fox Insight. All other author and non-author contributors are grant recipients from The Michael J. Fox Foundation. Members of the 23andMe Research Team are current or former employees of 23andMe, Inc., and hold stock or stock options in 23andMe.

Figures

Fig. 1
Fig. 1
Fox Insight Data flow.
See this image and copyright information in PMC

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