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Comment
. 2020 Dec 15;71(12):3152-3153.
doi: 10.1093/cid/ciz1236.

Has Pre-exposure Prophylaxis Made a Difference at a Population Level? Jury Is Still Out

Julia L Marcus  1 , A David Paltiel  2 , Rochelle P Walensky  3
Affiliations
Comment

Has Pre-exposure Prophylaxis Made a Difference at a Population Level? Jury Is Still Out

Julia L Marcus et al. Clin Infect Dis. .
No abstract available

Keywords: causality; confounding factors; epidemiologic; human immunodeficiency virus (HIV); pre-exposure prophylaxis (PrEP).

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References

    1. Grant RM, Lama JR, Anderson PL, et al. ; iPrEx Study Team Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med 2010; 363:2587–99. - PMC - PubMed
    1. Liu AY, Cohen SE, Vittinghoff E, et al. Preexposure prophylaxis for HIV infection integrated with municipal- and community-based sexual health services. JAMA Intern Med 2015; 176:75–84. - PMC - PubMed
    1. McCormack S, Dunn DT, Desai M, et al. Pre-exposure prophylaxis to prevent the acquisition of HIV-1 infection (PROUD): effectiveness results from the pilot phase of a pragmatic open-label randomised trial. Lancet 2016; 387:53–60. - PMC - PubMed
    1. Volk JE, Marcus JL, Phengrasamy T, et al. No new HIV infections with increasing use of HIV preexposure prophylaxis in a clinical practice setting. Clin Infect Dis 2015; 61:1601–3. - PMC - PubMed
    1. Marcus JL, Hurley LB, Nguyen DP, Silverberg MJ, Volk JE. Redefining human immunodeficiency virus (HIV) preexposure prophylaxis failures. Clin Infect Dis 2017; 65:1768–9. - PMC - PubMed

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