Chromosome Segregation: Evolving a Plastic Chromosome-Microtubule Interface
- PMID: 32097646
- DOI: 10.1016/j.cub.2019.12.058
Chromosome Segregation: Evolving a Plastic Chromosome-Microtubule Interface
Abstract
Despite a conserved requirement in mediating chromosome segregation, kinetochores display remarkable plasticity in their structure and composition. New work in holocentric insect species highlights the molecular rewiring that occurs when key structural components of the kinetochore are lost and centromere structure is changed.
Copyright © 2019 Elsevier Ltd. All rights reserved.
Comment on
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CenH3-Independent Kinetochore Assembly in Lepidoptera Requires CCAN, Including CENP-T.Curr Biol. 2020 Feb 24;30(4):561-572.e10. doi: 10.1016/j.cub.2019.12.014. Epub 2020 Feb 6. Curr Biol. 2020. PMID: 32032508
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