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Clinical Trial
. 1977 Jan;96(1):67-70.
doi: 10.1111/j.1365-2133.1977.tb05187.x.

A separation of clinical from epidermal thinning effect in the topical glucocorticoid clobetasone butyrate

D V Stevanovic, L Wilson, C G Sparkes
Clinical Trial

A separation of clinical from epidermal thinning effect in the topical glucocorticoid clobetasone butyrate

D V Stevanovic et al. Br J Dermatol. 1977 Jan.

Abstract

Clobetasone butyrate ointment has been shown to be more effective in treating psoriasis and eczema than flurandrenolone ointment yet to cause less epidermal thinning in a human experimental model. This is an indication that the clinical activity of topical glucocorticoids may not necessarily be inseparable from their propensity to cause atrophy of the skin.

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