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Review
. 2020 Apr;9(7):e1901553.
doi: 10.1002/adhm.201901553. Epub 2020 Feb 25.

Visible Light-Responsive Dynamic Biomaterials: Going Deeper and Triggering More

Teresa L Rapp  1 , Cole A DeForest  1   2   3   4
Affiliations
Review

Visible Light-Responsive Dynamic Biomaterials: Going Deeper and Triggering More

Teresa L Rapp et al. Adv Healthc Mater. 2020 Apr.

Abstract

Photoresponsive materials have been widely used in vitro for controlled therapeutic delivery and to direct 4D cell fate. Extension of the approaches into a bodily setting requires use of low-energy, long-wavelength light that penetrates deeper into and through complex tissue. This review details recent reports of photoactive small molecules and proteins that absorb visible and/or near-infrared light, opening the door to exciting new applications in multiplexed and in vivo regulation.

Keywords: drug delivery; hydrogels; low-energy light; multiplexing; phototriggers; tissue engineering; wavelength-selectivity.

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