mTORC2 Steals the Spotlight

Comment

Laura A Jansen. Epilepsy Curr. 2020 Mar.

. 2020 Mar;20(2):116-117.

doi: 10.1177/1535759720905835. Epub 2020 Feb 26.

Abstract

[Box: see text].

Therapeutic inhibition of mTORC2 rescues the behavioral and neurophysiological abnormalities associated with Pten-deficiency.
Chen CJ, Sgritta M, Mays J, Zhou H, Lucero R, Park J, Wang IC, Park JH, Kaipparettu BA, Stoica L, Jafar-Nejad P, Rigo F, Chin J, Noebels JL, Costa-Mattioli M. Chen CJ, et al. Nat Med. 2019 Nov;25(11):1684-1690. doi: 10.1038/s41591-019-0608-y. Epub 2019 Oct 21. Nat Med. 2019. PMID: 31636454 Free PMC article.

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