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Review
. 2020 Mar;33(2):98-108.
doi: 10.1055/s-0040-1701234. Epub 2020 Feb 25.

Hospital Infection Control: Clostridioides difficile

Nicholas A Turner  1   2 , Deverick J Anderson  1   2
Affiliations
Review

Hospital Infection Control: Clostridioides difficile

Nicholas A Turner et al. Clin Colon Rectal Surg. 2020 Mar.

Abstract

Clostridioides difficile remains a leading cause of healthcare-associated infection. Efforts at C. difficile prevention have been hampered by an increasingly complex understanding of transmission patterns and a high degree of heterogeneity among existing studies. Effective prevention of C. difficile infection requires multimodal interventions, including contact precautions, hand hygiene with soap and water, effective environmental cleaning, use of sporicidal cleaning agents, and antimicrobial stewardship. Roles for probiotics, avoidance of proton pump inhibitors, and isolation of asymptomatic carriers remain poorly defined.

Keywords: Clostridioides difficile; infection control; infection prevention.

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Conflict of interest statement

Conflict of Interest Dr. Anderson reports grants from AHRQ, grants from CDC, personal fees from UpToDate, Online, outside the submitted work.

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