Viral load of SARS-CoV-2 in clinical samples

doi:10.1016/S1473-3099(20)30113-4

. 2020 Apr;20(4):411-412.

doi: 10.1016/S1473-3099(20)30113-4. Epub 2020 Feb 24.

Viral load of SARS-CoV-2 in clinical samples

Yang Pan¹, Daitao Zhang², Peng Yang¹, Leo L M Poon³, Quanyi Wang⁴

Affiliations

¹ Beijing Center for Disease Prevention and Control, Beijing 100013, China; Beijing Research Center for Preventive Medicine, Beijing, China; School of Public Health, Capital Medical University, Beijing, China.
² Beijing Center for Disease Prevention and Control, Beijing 100013, China; Beijing Research Center for Preventive Medicine, Beijing, China.
³ School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region 999077, China. Electronic address: llmpoon@hku.hk.
⁴ Beijing Center for Disease Prevention and Control, Beijing 100013, China; Beijing Research Center for Preventive Medicine, Beijing, China. Electronic address: bjcdcxm@126.com.

PMID: 32105638
PMCID: PMC7128099
DOI: 10.1016/S1473-3099(20)30113-4

Viral load of SARS-CoV-2 in clinical samples

Yang Pan et al. Lancet Infect Dis. 2020 Apr.

. 2020 Apr;20(4):411-412.

doi: 10.1016/S1473-3099(20)30113-4. Epub 2020 Feb 24.

Authors

Yang Pan¹, Daitao Zhang², Peng Yang¹, Leo L M Poon³, Quanyi Wang⁴

Affiliations

¹ Beijing Center for Disease Prevention and Control, Beijing 100013, China; Beijing Research Center for Preventive Medicine, Beijing, China; School of Public Health, Capital Medical University, Beijing, China.
² Beijing Center for Disease Prevention and Control, Beijing 100013, China; Beijing Research Center for Preventive Medicine, Beijing, China.
³ School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region 999077, China. Electronic address: llmpoon@hku.hk.
⁴ Beijing Center for Disease Prevention and Control, Beijing 100013, China; Beijing Research Center for Preventive Medicine, Beijing, China. Electronic address: bjcdcxm@126.com.

PMID: 32105638
PMCID: PMC7128099
DOI: 10.1016/S1473-3099(20)30113-4

No abstract available

PubMed Disclaimer

Figures

**Figure**
Viral dynamics of SARS-CoV-2 in infected patients Viral load (mean [SD]) from serial throat swab and sputum samples in patient 1 (A) and patient 2 (B). (C) Viral load (median [IQR]) in throat and sputum samples collected from 80 patients at different stages after disease onset. (D) Correlation between viral load in throat swab samples and viral load in sputum samples.

See this image and copyright information in PMC

Comment in

Profile of specific antibodies to SARS-CoV-2: The first report.
Xiao AT, Gao C, Zhang S. Xiao AT, et al. J Infect. 2020 Jul;81(1):147-178. doi: 10.1016/j.jinf.2020.03.012. Epub 2020 Mar 21. J Infect. 2020. PMID: 32209385 Free PMC article. No abstract available.

Cited by

SARS-CoV-2 clearance in COVID-19 patients with Novaferon treatment: A randomized, open-label, parallel-group trial.
Zheng F, Zhou Y, Zhou Z, Ye F, Huang B, Huang Y, Ma J, Zuo Q, Tan X, Xie J, Niu P, Wang W, Xu Y, Peng F, Zhou N, Cai C, Tang W, Xiao X, Li Y, Zhou Z, Jiang Y, Xie Y, Tan W, Gong G. Zheng F, et al. Int J Infect Dis. 2020 Oct;99:84-91. doi: 10.1016/j.ijid.2020.07.053. Epub 2020 Aug 3. Int J Infect Dis. 2020. PMID: 32758689 Free PMC article. Clinical Trial.
Biosafety Risk Assessment of a Routine Diagnostic Laboratory During the Coronavirus Disease 2019 Pandemic.
Zorbozan O, Zorbozan N, Turgay N. Zorbozan O, et al. Appl Biosaf. 2021 Sep;26(Suppl 1):S2-S9. doi: 10.1089/apb.20.0064. Epub 2021 Sep 13. Appl Biosaf. 2021. PMID: 36032648 Free PMC article.
Shedding of SARS-CoV-2 in feces and urine and its potential role in person-to-person transmission and the environment-based spread of COVID-19.
Jones DL, Baluja MQ, Graham DW, Corbishley A, McDonald JE, Malham SK, Hillary LS, Connor TR, Gaze WH, Moura IB, Wilcox MH, Farkas K. Jones DL, et al. Sci Total Environ. 2020 Dec 20;749:141364. doi: 10.1016/j.scitotenv.2020.141364. Epub 2020 Jul 31. Sci Total Environ. 2020. PMID: 32836117 Free PMC article. Review.
The first case study of wastewater-based epidemiology of COVID-19 in Hong Kong.
Xu X, Zheng X, Li S, Lam NS, Wang Y, Chu DKW, Poon LLM, Tun HM, Peiris M, Deng Y, Leung GM, Zhang T. Xu X, et al. Sci Total Environ. 2021 Oct 10;790:148000. doi: 10.1016/j.scitotenv.2021.148000. Epub 2021 May 24. Sci Total Environ. 2021. PMID: 34091338 Free PMC article.
Fighting COVID-19: Integrated Micro- and Nanosystems for Viral Infection Diagnostics.
Qin Z, Peng R, Baravik IK, Liu X. Qin Z, et al. Matter. 2020 Sep 2;3(3):628-651. doi: 10.1016/j.matt.2020.06.015. Epub 2020 Jul 9. Matter. 2020. PMID: 32838297 Free PMC article. Review.

See all "Cited by" articles

References

1. Lu R, Zhao X, Li J. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020 doi: 10.1016/S0140-6736(20)30251-8. published online Jan 30. - DOI - PMC - PubMed
1. WHO Laboratory testing for 2019 novel coronavirus (2019-nCoV) in suspected human cases. Interim guidance. Jan 17, 2020. https://www.who.int/publications-detail/laboratory-testing-for-2019-nove...
1. Chu DKW, Pan Y, Cheng SMS. Molecular diagnosis of a novel coronavirus (2019-nCoV) causing an outbreak of pneumonia. Clin Chem. 2020 doi: 10.1093/clinchem/hvaa029. published online Jan 31. - DOI - PMC - PubMed
1. Peiris JS, Chu CM, Cheng VC. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. Lancet. 2003;361:1767–1772. - PMC - PubMed

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
Other Literature Sources
- The Lens - Patent Citations Database
Medical
- ClinicalTrials.gov
Miscellaneous
- NCI CPTAC Assay Portal

[1] Lu R, Zhao X, Li J. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020 doi: 10.1016/S0140-6736(20)30251-8. published online Jan 30. - DOI - PMC - PubMed

[2] Lu R, Zhao X, Li J. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020 doi: 10.1016/S0140-6736(20)30251-8. published online Jan 30. - DOI - PMC - PubMed

[3] WHO Laboratory testing for 2019 novel coronavirus (2019-nCoV) in suspected human cases. Interim guidance. Jan 17, 2020. https://www.who.int/publications-detail/laboratory-testing-for-2019-nove...

[4] WHO Laboratory testing for 2019 novel coronavirus (2019-nCoV) in suspected human cases. Interim guidance. Jan 17, 2020. https://www.who.int/publications-detail/laboratory-testing-for-2019-nove...

[5] Chu DKW, Pan Y, Cheng SMS. Molecular diagnosis of a novel coronavirus (2019-nCoV) causing an outbreak of pneumonia. Clin Chem. 2020 doi: 10.1093/clinchem/hvaa029. published online Jan 31. - DOI - PMC - PubMed

[6] Chu DKW, Pan Y, Cheng SMS. Molecular diagnosis of a novel coronavirus (2019-nCoV) causing an outbreak of pneumonia. Clin Chem. 2020 doi: 10.1093/clinchem/hvaa029. published online Jan 31. - DOI - PMC - PubMed

[7] Peiris JS, Chu CM, Cheng VC. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. Lancet. 2003;361:1767–1772. - PMC - PubMed

[8] Peiris JS, Chu CM, Cheng VC. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. Lancet. 2003;361:1767–1772. - PMC - PubMed

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Viral load of SARS-CoV-2 in clinical samples

Affiliations

Viral load of SARS-CoV-2 in clinical samples

Authors

Affiliations

Figures

Comment in

Similar articles

Cited by

References

Publication types

MeSH terms

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Miscellaneous